Ostalo
Bowenoid Papulosis in a Patient with AIDS Treated with Imiquimod: Case Report
Mariana de Gusmao Nunes
; Sector of Dermatology, HUCFF-UFRJ and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Beatriz Mortiz Trope
; Sector of Dermatology, HUCFF-UFRJ and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Silvia Maria Baeta Cavalcanti
; Department of Microbiology and Parasitology, Biomedical Institute, Universidade Federal Fluminense, Niteroi, Brazil
Ledy do Horto dos Santos Oliveira
; Sector of Dermatology, HUCFF-UFRJ and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Marcia Ramos-e-Silva
orcid.org/0000-0003-1625-0760
; Sector of Dermatology, HUCFF-UFRJ and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Sažetak
A 53-year-old male patient with acquired immunodeficiency
syndrome (AIDS) was treated with topical immunomodulator imiquimod
for bowenoid papular. Clinically the lesions presented as condilomatous
and papulous changes with color varying from skin color to gray ish. The
lesions were located in the glans and in the dorsum of the penis. Clinical
diagnosis was confirmed by histopathological examination, and the
polymerase chain reaction (PCR) demonstrated the presence of human
papilloma virus (HPV) 16. It was decided to apply a topical treatment
with imiquimod 5% cream three times a week for 16 weeks. Al most
complete regression was obtained; the residual lesions were treated
with a combined chemical cauterization by using 50% trichloroacetic
acid followed by 25% podophylin. Although it is not a definitive treatment, the use of topical immunomodulator is one more therapeutic option in the selected HPV cases.
Ključne riječi
adjuvants, immunologic; Bowen´s disease; condylomata acuminata; human papilloma virus; penile neoplasms
Hrčak ID:
88553
URI
Datum izdavanja:
1.4.2004.
Posjeta: 972 *