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PARANEOPLASTIC LIMBIC ENCEPHALITIS

VIŠNJA NESEK ADAM ; University Department of Anesthesiology; Resuscitation and Intensive Care; Sveti Duh University Hospital; Zagreb; Croatia
DAMJAN MARIN ; University Department of Anesthesiology; Resuscitation and Intensive Care; Sveti Duh University Hospital; Zagreb; Croatia
HRVOJE BUDINČEVIĆ ; University Department of Neurology; Sveti Duh University Hospital; Zagreb; Croatia
VIVIANA MRŠIĆ ; University Department of Anesthesiology; Resuscitation and Intensive Care; Sveti Duh University Hospital; Zagreb; Croatia
TANJA GORANOVIĆ ; University Department of Anesthesiology; Resuscitation and Intensive Care; Sveti Duh University Hospital; Zagreb; Croatia
DINKO TONKOVIĆ ; University Department of Anesthesiology; Resuscitation and Intensive Care; Sveti Duh University Hospital; Zagreb; Croatia

Puni tekst: hrvatski, pdf (237 KB) str. 29-32 preuzimanja: 2.270* citiraj
APA 6th Edition
NESEK ADAM, V., MARIN, D., BUDINČEVIĆ, H., MRŠIĆ, V., GORANOVIĆ, T. i TONKOVIĆ, D. (2012). PARANEOPLASTIČKI LIMBIČKI ENCEFALITIS. Acta medica Croatica, 66 (1), 29-32. Preuzeto s https://hrcak.srce.hr/93169
MLA 8th Edition
NESEK ADAM, VIŠNJA, et al. "PARANEOPLASTIČKI LIMBIČKI ENCEFALITIS." Acta medica Croatica, vol. 66, br. 1, 2012, str. 29-32. https://hrcak.srce.hr/93169. Citirano 21.10.2019.
Chicago 17th Edition
NESEK ADAM, VIŠNJA, DAMJAN MARIN, HRVOJE BUDINČEVIĆ, VIVIANA MRŠIĆ, TANJA GORANOVIĆ i DINKO TONKOVIĆ. "PARANEOPLASTIČKI LIMBIČKI ENCEFALITIS." Acta medica Croatica 66, br. 1 (2012): 29-32. https://hrcak.srce.hr/93169
Harvard
NESEK ADAM, V., et al. (2012). 'PARANEOPLASTIČKI LIMBIČKI ENCEFALITIS', Acta medica Croatica, 66(1), str. 29-32. Preuzeto s: https://hrcak.srce.hr/93169 (Datum pristupa: 21.10.2019.)
Vancouver
NESEK ADAM V, MARIN D, BUDINČEVIĆ H, MRŠIĆ V, GORANOVIĆ T, TONKOVIĆ D. PARANEOPLASTIČKI LIMBIČKI ENCEFALITIS. Acta medica Croatica [Internet]. 2012 [pristupljeno 21.10.2019.];66(1):29-32. Dostupno na: https://hrcak.srce.hr/93169
IEEE
V. NESEK ADAM, D. MARIN, H. BUDINČEVIĆ, V. MRŠIĆ, T. GORANOVIĆ i D. TONKOVIĆ, "PARANEOPLASTIČKI LIMBIČKI ENCEFALITIS", Acta medica Croatica, vol.66, br. 1, str. 29-32, 2012. [Online]. Dostupno na: https://hrcak.srce.hr/93169. [Citirano: 21.10.2019.]

Sažetak
Paraneoplastic limbic encephalitis (PLE) is a condition characterized by nervous system damage or dysfunction without indication that the nervous system is directly affected by tumor cells. Since it is clinically presented with an array of neuropsychiatric symptoms that usually precede the occurrence of malignant disease; and because of mimicking a psychiatric disease; it can
sometimes make the diagnosis difficult and can be overlooked. Typical presentations consist of progressive confusion and deficits in short-term memory; which worsen over days to weeks. The current hypothesis on the pathogenesis of PLE implicates an autoimmune process involving antigens shared by tumor cells and neuronal cells in limbic structures. It has been considered that
the autoantibodies cross-react with antigens on normal cells such as the neurons; resulting in cytotoxicity; or they can form complexes with a circulating antigen to induce organ damage through immune complex deposition. The treatment of PLE involves underlying cancer removal by surgery; chemotherapy; radiotherapy or hormonal treatment; and immunosuppressive therapy. Unfortunately; this therapy combination is still generally unsatisfactory. Although PLE is a relatively rare neurologic disorder; because of its association with malignancies and difficulty in diagnosing; this article gives a brief review of the literature and summarizes current knowledge of this syndrome.

Ključne riječi
encephalitis; paraneoplastic syndrome

Hrčak ID: 93169

URI
https://hrcak.srce.hr/93169

[hrvatski]

Posjeta: 3.139 *