Kratko priopćenje
Ectopic Pregnancy as Contraceptive Failure in Patient with Epilepsy
Branko Radakovic
; University of Zagreb, School of Medicine, Department for Gynecology and Obstetrics, Zagreb, Croatia
Marina Sprem Goldstajn
; University of Zagreb, School of Medicine, Department for Gynecology and Obstetrics, Zagreb, Croatia
Sažetak
Epilepsy is a common neurologic condition which includes many women’s health issues. Menstrual disorders, reproductive endocrinological disturbances, ovulatory dysfunction and infertility appear to be relatively frequent in women with epilepsy. Clinical decision making which contraceptive regimen is optimal for an individual woman with epilepsy is one of the most challenging tasks when taking care of women with epilepsy. A higher incidence of breakthrough bleeding and contraceptive failure was determined among women using antiepileptic drugs. There is the increased risk for contraceptive failure with the use of P450 3A4 enzyme-inducing antiepileptic drugs (AEDs) such as phenobarbital, carbamazepine, phenytoin, felbamate, topiramate and oxcarbazepine. Therefore, it is recommended to use noninducing AEDs, or for those who use inducing AEDs, the use of oral hormonal contraceptive pills which contained equal or more than 50 mg of estrogen, or intrauterine devices. The aim of the article is to present woman with epilepsy who was used combined low dose oral contraceptive pills containing 20 mg of ethinyl estradiol which in interaction with carbamazepine resulted with ectopic tubar pregnancy.
Ključne riječi
tubar pregnancy; epilepsy; oral contraceptives; drug interaction
Hrčak ID:
95025
URI
Datum izdavanja:
27.12.2012.
Posjeta: 963 *