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Acta Pharmaceutica, Vol. 63 No. 2, 2013.

Kratko priopćenje
https://doi.org/10.2478/acph-2013-0016

Synthesis and potential antimicrobial studies on some Mannich bases carrying imidazole moiety

PRIYA VINEETHA FRANK ; Department of Chemistry, Canara Engineering College, Benjanapadavu, Mangalore-574219, Karnataka, India
MAHESHA MANJUNATHA POOJARY ; Department of Chemistry, Canara Engineering College, Benjanapadavu, Mangalore-574219, Karnataka, India
NARAL DAMODARA ; Department of Chemistry, Canara Engineering College, Benjanapadavu, Mangalore-574219, Karnataka, India
CHANDRASHEKHAR CHIKKANNA ; PG Department of Medicinal Chemistry, SDM College, Ujire-574240, Karnataka, India

Puni tekst: engleski, pdf (135 KB) str. 231-239 preuzimanja: 1.038* citiraj
APA 6th Edition
FRANK, P.V., POOJARY, M.M., DAMODARA, N. i CHIKKANNA, C. (2013). Synthesis and potential antimicrobial studies on some Mannich bases carrying imidazole moiety. Acta Pharmaceutica, 63 (2), 231-239. https://doi.org/10.2478/acph-2013-0016
MLA 8th Edition
FRANK, PRIYA VINEETHA, et al. "Synthesis and potential antimicrobial studies on some Mannich bases carrying imidazole moiety." Acta Pharmaceutica, vol. 63, br. 2, 2013, str. 231-239. https://doi.org/10.2478/acph-2013-0016. Citirano 16.02.2019.
Chicago 17th Edition
FRANK, PRIYA VINEETHA, MAHESHA MANJUNATHA POOJARY, NARAL DAMODARA i CHANDRASHEKHAR CHIKKANNA. "Synthesis and potential antimicrobial studies on some Mannich bases carrying imidazole moiety." Acta Pharmaceutica 63, br. 2 (2013): 231-239. https://doi.org/10.2478/acph-2013-0016
Harvard
FRANK, P.V., et al. (2013). 'Synthesis and potential antimicrobial studies on some Mannich bases carrying imidazole moiety', Acta Pharmaceutica, 63(2), str. 231-239. doi: https://doi.org/10.2478/acph-2013-0016
Vancouver
FRANK PV, POOJARY MM, DAMODARA N, CHIKKANNA C. Synthesis and potential antimicrobial studies on some Mannich bases carrying imidazole moiety. Acta Pharm. [Internet]. 2013 [pristupljeno 16.02.2019.];63(2):231-239. doi: https://doi.org/10.2478/acph-2013-0016
IEEE
P.V. FRANK, M.M. POOJARY, N. DAMODARA i C. CHIKKANNA, "Synthesis and potential antimicrobial studies on some Mannich bases carrying imidazole moiety", Acta Pharmaceutica, vol.63, br. 2, str. 231-239, 2013. [Online]. doi: https://doi.org/10.2478/acph-2013-0016

Sažetak
Starting from 2-methyl-4-nitro-imidazole, new 5-(2-methyl-4-nitro-1-imidazomethyl)-1,3,4-oxadiazole-2-thione (3) was synthesized and was subjected to Mannich reaction with appropriate amines to yield a new series of 3-substituted aminomethyl-5-(2-methyl-4-nitro-1-imidazomethyl)-1,3,4-oxadiazole-2-thiones (4a-j). The structure of the title compounds was elucidated by elemental analysis and spectral data. The newly synthesized Mannich bases were screened for their antibacterial and antifungal activity. Many of these compounds exhibited potent antifungal activity.

Ključne riječi
imidazole derivatives; Mannich bases; oxadiazole; antibacterial activity; antifungal activity

Hrčak ID: 97700

URI
https://hrcak.srce.hr/97700

Posjeta: 1.208 *