Paediatria Croatica, Vol. 56 No. 4, 2013.
Izvorni znanstveni članak
BIRTH WEIGHT OF IRANIAN CHILDREN WITH PHENYLKETONURIA
Farzaneh Rohani
; Endocrine Research Centre (Firouzgar), Institute of Endocrinology and Metabolism (Hemmat Campus) and Department of Pediatric Endocrinology and Metabolic diseases, Ali Asghar Children Hospital, Tehran University of Medical Sciences, Tehran, Iran
Mohammadreza Alaei
; Department of Pediatric Endocrinology and Metabolic diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Glareh Totonchi
; Shahid Beheshti University of Medical Sciences, Tehran, Iran
Eznollah Azargashb
; Shahid Beheshti University of Medical Sciences, Tehran, Iran
Sažetak
To assess whether birth weight is affected in Iranian patients with phenylketonuria, birth weights of 118 patients with phenylketonuria were compared with 264 healthy controls matched by gestational age and sex, and with patients unaffected siblings. The mean (±SD) birth weight of phenylketonuria patients and control group was 3199.5 (±554.5) and 3260.3 (±483.2) grams, respectively. The mean birth weight of phenylketonuria patients was by 60.7 lower as compared with controls (p=0.27). There was no significant correlation between disease severity and phenylketonuria patient birth weight (p=0.55). The mean (±SD) birth weight of 59 phenylketonuria patients and their siblings was 3193.2 (±568.6) and 3083.9 (±514.0)g, respectively. The mean birth weight of phenylketonuria patients was by 109 g greater as compared with their siblings (p=0.271). Birth weight of Iranian phenylketonuria patients was not significantly lower as compared with their healthy siblings and normal population. Although control infants had a slightly greater birth weight than phenylketonuria infants and phenylketonuria infants had a slightly greater birth weight than their unaffected siblings, the difference was not statistically significant. Furthermore, birth weight was not affected by the disease severity.
Ključne riječi
Descriptors: PHENYLKETONURIAS; BIRTH WEIGHT; IRAN
Hrčak ID:
98774
URI
Datum izdavanja:
16.12.2012.
Posjeta: 652 *