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INVASIVE TRICHOSPORONOSIS CAUSED BY TRICHOSPORON ASAHII IN A POLYTRAUMATIZED NEUROSURGICAL PATIENT: CASE REPORT

MAJA TOMIĆ PARADŽIK ; Department of Microbiology, Institute of Public Health, Brod-Posavina County,Slavonski Brod, Croatia
JOSIP MIHIĆ ; Section of Neurosurgery, Department of Surgery, Dr. Josip Benčević General Hospital, Slavonski Brod, Croatia
JASMINKA KOPIĆ ; Department of Anesthesiology, Resuscitation and Intensive Care, Dr. Josip Benčević General Hospital,
EMILIJA MLINARIĆ MISSONI ; Department of Mycology, Croatian Institute of Public Health, Zagreb, Croatia

Puni tekst: hrvatski, pdf (137 KB) str. 397-401 preuzimanja: 410* citiraj
APA 6th Edition
TOMIĆ PARADŽIK, M., MIHIĆ, J., KOPIĆ, J. i MLINARIĆ MISSONI, E. (2012). INVAZIVNA TRIHOSPORONOZA UZROKOVANA GLJIVOM TRICHOSPORON ASAHII U POLITRAUMATIZIRANOG NEUROKIRURŠKOG BOLESNIKA. Acta medica Croatica, 66 (5), 397-401. Preuzeto s https://hrcak.srce.hr/104185
MLA 8th Edition
TOMIĆ PARADŽIK, MAJA, et al. "INVAZIVNA TRIHOSPORONOZA UZROKOVANA GLJIVOM TRICHOSPORON ASAHII U POLITRAUMATIZIRANOG NEUROKIRURŠKOG BOLESNIKA." Acta medica Croatica, vol. 66, br. 5, 2012, str. 397-401. https://hrcak.srce.hr/104185. Citirano 11.12.2019.
Chicago 17th Edition
TOMIĆ PARADŽIK, MAJA, JOSIP MIHIĆ, JASMINKA KOPIĆ i EMILIJA MLINARIĆ MISSONI. "INVAZIVNA TRIHOSPORONOZA UZROKOVANA GLJIVOM TRICHOSPORON ASAHII U POLITRAUMATIZIRANOG NEUROKIRURŠKOG BOLESNIKA." Acta medica Croatica 66, br. 5 (2012): 397-401. https://hrcak.srce.hr/104185
Harvard
TOMIĆ PARADŽIK, M., et al. (2012). 'INVAZIVNA TRIHOSPORONOZA UZROKOVANA GLJIVOM TRICHOSPORON ASAHII U POLITRAUMATIZIRANOG NEUROKIRURŠKOG BOLESNIKA', Acta medica Croatica, 66(5), str. 397-401. Preuzeto s: https://hrcak.srce.hr/104185 (Datum pristupa: 11.12.2019.)
Vancouver
TOMIĆ PARADŽIK M, MIHIĆ J, KOPIĆ J, MLINARIĆ MISSONI E. INVAZIVNA TRIHOSPORONOZA UZROKOVANA GLJIVOM TRICHOSPORON ASAHII U POLITRAUMATIZIRANOG NEUROKIRURŠKOG BOLESNIKA. Acta medica Croatica [Internet]. 2012 [pristupljeno 11.12.2019.];66(5):397-401. Dostupno na: https://hrcak.srce.hr/104185
IEEE
M. TOMIĆ PARADŽIK, J. MIHIĆ, J. KOPIĆ i E. MLINARIĆ MISSONI, "INVAZIVNA TRIHOSPORONOZA UZROKOVANA GLJIVOM TRICHOSPORON ASAHII U POLITRAUMATIZIRANOG NEUROKIRURŠKOG BOLESNIKA", Acta medica Croatica, vol.66, br. 5, str. 397-401, 2012. [Online]. Dostupno na: https://hrcak.srce.hr/104185. [Citirano: 11.12.2019.]

Sažetak
Trichosporon asahii (formerly T. beigelii) is a rare cause of human infections with very varied clinical manifestations ranging from superficial infections to severe and systemic diseases. T. asahii is a life-threatening opportunistic pathogen especially for granulocytopenic, immunocompromised and immunodeficient patients. It is the possible cause of summer-type hypersensitivity pneumonitis in Japan and systemic infections in transplant patients, patients on corticosteroid therapy, patients with solid tumors and burn patients. Cases of infection in non-immunocompromised surgical patients and patients with long-term stay in ICU are described in the literature. We report on T. asahii fungemia in a polytraumatized neurosurgical patient with long-term stay in the hospital. Urinary tract was the source of fungemia, with the same pathogen isolated from urine and blood at the same time. In the Referral Center for Systemic Mycoses, Croatian Institute of Public Health, Zagreb, the strain from the urine and blood culture was identified as T. asahii, with good susceptibility to fluconazole, voriconazole and 5 fluorocytosine, reduced susceptibility to itraconazole and resistance to amphotericin B. The patient responded to fluconazole therapy very well. Since systemic trichosporonoses are generally associated with immunocompromised patients (hematologic, granulocytopenic and AIDS patients), thiscase confirms the possibility of infection with this pathogen in patients with long-term hospital stay and reduced local immunity, but without classic immunodeficiency.

Ključne riječi
invasive trichosporonosis; polytrauma; Trichosporon asahii

Hrčak ID: 104185

URI
https://hrcak.srce.hr/104185

[hrvatski]

Posjeta: 625 *