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https://doi.org/10.5562/cca2064

Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles

Serap Yilmaz ; Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100, Tandoğan, Ankara, Turkey
Ismail Yalcin ; Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100, Tandoğan, Ankara, Turkey
Fatma Kaynak-Onurdag ; Gazi University, Faculty of Pharmacy, Department of Pharmaceutical Microbiology, 06330, Etiler, Ankara, Turkey
Ilkay Yildiz ; Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100, Tandoğan, Ankara, Turkey
Esin Aki ; Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100, Tandoğan, Ankara, Turkey

Puni tekst: engleski, pdf (2 MB) str. 223-231 preuzimanja: 1.008* citiraj
APA 6th Edition
Yilmaz, S., Yalcin, I., Kaynak-Onurdag, F., Yildiz, I. i Aki, E. (2013). Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles. Croatica Chemica Acta, 86 (2), 223-231. https://doi.org/10.5562/cca2064
MLA 8th Edition
Yilmaz, Serap, et al. "Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles." Croatica Chemica Acta, vol. 86, br. 2, 2013, str. 223-231. https://doi.org/10.5562/cca2064. Citirano 01.10.2020.
Chicago 17th Edition
Yilmaz, Serap, Ismail Yalcin, Fatma Kaynak-Onurdag, Ilkay Yildiz i Esin Aki. "Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles." Croatica Chemica Acta 86, br. 2 (2013): 223-231. https://doi.org/10.5562/cca2064
Harvard
Yilmaz, S., et al. (2013). 'Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles', Croatica Chemica Acta, 86(2), str. 223-231. https://doi.org/10.5562/cca2064
Vancouver
Yilmaz S, Yalcin I, Kaynak-Onurdag F, Yildiz I, Aki E. Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles. Croatica Chemica Acta [Internet]. 2013 [pristupljeno 01.10.2020.];86(2):223-231. https://doi.org/10.5562/cca2064
IEEE
S. Yilmaz, I. Yalcin, F. Kaynak-Onurdag, I. Yildiz i E. Aki, "Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles", Croatica Chemica Acta, vol.86, br. 2, str. 223-231, 2013. [Online]. https://doi.org/10.5562/cca2064

Sažetak
A new series of 2-[4-(4-substitutedbenzamido / phenylacetamido / phenylpropionamido) benzyl
/ phenyl]benzothiazole derivatives (6a−6w) were synthesized and evaluated for antibacterial and antifungal
activities against Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Pseudomonas
aeruginosa, Escherichia coli with their drug-resistant isolates and a yeast Candida albicans. Microbiological
results indicated that the compounds possessed a broad spectrum of activity against the tested microorganisms
at MIC values between 200 and 6.25 μg/ml. Compounds 6e and 6j exhibited the greatest activity
with MIC values of 6.25 μg/ml against Pseudomonas aeruginosa, and Staphylococcus aureus isolate,
respectively.(doi: 10.5562/cca2064)

Ključne riječi
benzothiazole; antibacterial activity; antifungal activity; multi-drug resistance

Hrčak ID: 105598

URI
https://hrcak.srce.hr/105598

Posjeta: 1.317 *