The Risk of Developing Endemic Nephropathy in Subjects with Proteinuria
; Institute of Public Health of Brod-Posavina County, Slavonski Brod, Croatia
; University of Zagreb, School of Medicine, »Andrija Štampar« School of Public Health, Department for Medical Statistics, Epidemiology and Medical Informatics, Zagreb, Croatia
; Clinical Hospital Center Zagreb, Zagreb, Croatia
APA 6th Edition Cvitković, A., Sonicki, Z. i Čvoriščec, D. (2014). The Risk of Developing Endemic Nephropathy in Subjects with Proteinuria. Collegium antropologicum, 38 (1), 155-159. Preuzeto s https://hrcak.srce.hr/120871
MLA 8th Edition Cvitković, Ante, et al. "The Risk of Developing Endemic Nephropathy in Subjects with Proteinuria." Collegium antropologicum, vol. 38, br. 1, 2014, str. 155-159. https://hrcak.srce.hr/120871. Citirano 29.07.2021.
Chicago 17th Edition Cvitković, Ante, Zdenko Sonicki i Dubravka Čvoriščec. "The Risk of Developing Endemic Nephropathy in Subjects with Proteinuria." Collegium antropologicum 38, br. 1 (2014): 155-159. https://hrcak.srce.hr/120871
Harvard Cvitković, A., Sonicki, Z., i Čvoriščec, D. (2014). 'The Risk of Developing Endemic Nephropathy in Subjects with Proteinuria', Collegium antropologicum, 38(1), str. 155-159. Preuzeto s: https://hrcak.srce.hr/120871 (Datum pristupa: 29.07.2021.)
Vancouver Cvitković A, Sonicki Z, Čvoriščec D. The Risk of Developing Endemic Nephropathy in Subjects with Proteinuria. Collegium antropologicum [Internet]. 2014 [pristupljeno 29.07.2021.];38(1):155-159. Dostupno na: https://hrcak.srce.hr/120871
IEEE A. Cvitković, Z. Sonicki i D. Čvoriščec, "The Risk of Developing Endemic Nephropathy in Subjects with Proteinuria", Collegium antropologicum, vol.38, br. 1, str. 155-159, 2014. [Online]. Dostupno na: https://hrcak.srce.hr/120871. [Citirano: 29.07.2021.]
Sažetak Endemic nephropathy is a chronic tubulointerstitial disease characterized by early damage to the proximal tubule, with low-molecular weight proteinuria being an important hallmark and possible tool for early diagnosis. The aim of this retrospective cohort study was to assess the risk of developing endemic nephropathy in subjects with proteinuria from the endemic region in Croatia. The cohort study included subjects with proteinuria determined by the sulfosalicylic acid method (after 1988 with strip method), involved in the field survey conducted in the Croatian endemic village of Kaniža in 1975 and followed up until 1997. Subjects with endemic nephropathy established at the first visit and patients that failed to present for follow up visits after 1975. were excluded. In the field survey group that consisted of 624 subjects (286 male and 338 female), proteinuria was established in 157 subjects. Upon the application of exclusion and inclusion criteria, the study cohort included 111 of 157 subjects. The mean follow up was 7.26 years (95% confidence interval 4.06-10.46 years). During the follow up period, 19 (17%) subjects with initial proteinuria developed endemic nephropathy. The incidence density of endemic nephropathy among subjects with proteinuria was 1.3 per 100 persons/year. Estimated risk was 0.0137 (confidence interval 0.0087-0.0214) per year of exposure. The presence of proteinuria determined by the sulfosalicylic acid or test strip in subjects from the endemic village indicated that endemic nephropathy would develop in 1.3 of 100 subjects with proteinuria per year.