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Comparison of minimum effective volume of local anesthetic for ultrasound guided supraclavicular block (MEAV95) in elderly and middle aged patients

JADRANKA PAVIČIĆ ŠARIĆ   ORCID icon orcid.org/0000-0003-4124-8056 ; Department of Anesthesiology and Intensive Care University Hospital Merkur, Zajčeva 19, 10000 Zagreb, Croatia
VINKO VIDJAK ; Department of Diagnostic and Interventional Radiology University Hospital Merkur, Zagreb, Croatia
JELENA ZENKO ; Department of Anesthesiology and Intensive Care University Hospital Merkur, Zagreb, Croatia
MATEA BOGDANOVIĆ DVORŠČAK ; Department of Anesthesiology and Intensive Care University Hospital Merkur, Zagreb, Croatia
VANJA VONČINA ; Department of Anesthesiology and Intensive Care University Hospital Merkur, Zagreb, Croatia
NATAŠA PAKLAR ; Department of Anesthesiology and Intensive Care University Hospital Merkur, Zagreb, Croatia

Puni tekst: engleski, pdf (944 KB) str. 273-276 preuzimanja: 408* citiraj
APA 6th Edition
PAVIČIĆ ŠARIĆ, J., VIDJAK, V., ZENKO, J., BOGDANOVIĆ DVORŠČAK, M., VONČINA, V. i PAKLAR, N. (2015). Comparison of minimum effective volume of local anesthetic for ultrasound guided supraclavicular block (MEAV95) in elderly and middle aged patients. Periodicum biologorum, 117 (2), 273-276. Preuzeto s https://hrcak.srce.hr/142924
MLA 8th Edition
PAVIČIĆ ŠARIĆ, JADRANKA, et al. "Comparison of minimum effective volume of local anesthetic for ultrasound guided supraclavicular block (MEAV95) in elderly and middle aged patients." Periodicum biologorum, vol. 117, br. 2, 2015, str. 273-276. https://hrcak.srce.hr/142924. Citirano 25.02.2020.
Chicago 17th Edition
PAVIČIĆ ŠARIĆ, JADRANKA, VINKO VIDJAK, JELENA ZENKO, MATEA BOGDANOVIĆ DVORŠČAK, VANJA VONČINA i NATAŠA PAKLAR. "Comparison of minimum effective volume of local anesthetic for ultrasound guided supraclavicular block (MEAV95) in elderly and middle aged patients." Periodicum biologorum 117, br. 2 (2015): 273-276. https://hrcak.srce.hr/142924
Harvard
PAVIČIĆ ŠARIĆ, J., et al. (2015). 'Comparison of minimum effective volume of local anesthetic for ultrasound guided supraclavicular block (MEAV95) in elderly and middle aged patients', Periodicum biologorum, 117(2), str. 273-276. Preuzeto s: https://hrcak.srce.hr/142924 (Datum pristupa: 25.02.2020.)
Vancouver
PAVIČIĆ ŠARIĆ J, VIDJAK V, ZENKO J, BOGDANOVIĆ DVORŠČAK M, VONČINA V, PAKLAR N. Comparison of minimum effective volume of local anesthetic for ultrasound guided supraclavicular block (MEAV95) in elderly and middle aged patients. Periodicum biologorum [Internet]. 2015 [pristupljeno 25.02.2020.];117(2):273-276. Dostupno na: https://hrcak.srce.hr/142924
IEEE
J. PAVIČIĆ ŠARIĆ, V. VIDJAK, J. ZENKO, M. BOGDANOVIĆ DVORŠČAK, V. VONČINA i N. PAKLAR, "Comparison of minimum effective volume of local anesthetic for ultrasound guided supraclavicular block (MEAV95) in elderly and middle aged patients", Periodicum biologorum, vol.117, br. 2, str. 273-276, 2015. [Online]. Dostupno na: https://hrcak.srce.hr/142924. [Citirano: 25.02.2020.]

Sažetak
Backgrund and purpose: The aim of this study was to determine the
minimum effective volume of local anesthetic (LA) required to produce an
efficient supraclavicular block in 95% of patients (MEAV95) using an ultrasound (US)-guided technique in an elderly (>65 y) and a middle aged
group (<45 y) of patients. Furthermore, we aimed to calculate potency ratio of LA between the groups. We assumed a reduced MEAV95 in elderly group.

Matherials and Methods: Fourty-four patients (N=22 per group) undergoing upper limb surgery received a US-guided supraclavicular block.
The study method is a previously validated step-up/step-down sequential
model where the volume of LA for each following patient is determined
according to the outcome of the previous block. The starting volume was 30 mL; in the case of block failure, the volume was increased by 5 ml. After successful block, the volume was reduced by 5 mL. MEAV95 was calculated using probit transformation and logistic regression. Potency ratio of LA is calculated using Fieller’s method.

Results and Conclusions: The calculated minimum effective anesthetic
volume in 95% of patients was 16.49 mL (95% CI, 12.23–20.75
mL) in elderly and 44.52 mL (95% CI, 19.05–69.99 mL) in middle aged
group (95% CI, 0.7–55.3 mL, P=0.044). A potency ratio of LA between
middle aged and elderly is 2.69 (95% CI 2.13 to 3.44). The minimum
volume requirement for effective US-guided supraclavicular block in 95%
of elderly patients was significantly reduced. A potency ratio of 2.69 indicates almost three times stronger LA potency in the elderly.

Hrčak ID: 142924

URI
https://hrcak.srce.hr/142924

Posjeta: 541 *