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Pregledni rad
https://doi.org/10.1515/acph-2016-0003

Microscopic methods in analysis of submicron phospholipid dispersions

MARCIN PLACZEK ; Department of Pharmaceutical Technology, Medical University of Gdańsk, Poland
MAGDALENA KOSELA ; Department of Pharmaceutical Technology, Medical University of Gdańsk, Poland

Puni tekst: engleski, pdf (3 MB) str. 1-22 preuzimanja: 1.225* citiraj
APA 6th Edition
PLACZEK, M. i KOSELA, M. (2016). Microscopic methods in analysis of submicron phospholipid dispersions. Acta Pharmaceutica, 66 (1), 1-22. https://doi.org/10.1515/acph-2016-0003
MLA 8th Edition
PLACZEK, MARCIN i MAGDALENA KOSELA. "Microscopic methods in analysis of submicron phospholipid dispersions." Acta Pharmaceutica, vol. 66, br. 1, 2016, str. 1-22. https://doi.org/10.1515/acph-2016-0003. Citirano 24.08.2019.
Chicago 17th Edition
PLACZEK, MARCIN i MAGDALENA KOSELA. "Microscopic methods in analysis of submicron phospholipid dispersions." Acta Pharmaceutica 66, br. 1 (2016): 1-22. https://doi.org/10.1515/acph-2016-0003
Harvard
PLACZEK, M., i KOSELA, M. (2016). 'Microscopic methods in analysis of submicron phospholipid dispersions', Acta Pharmaceutica, 66(1), str. 1-22. https://doi.org/10.1515/acph-2016-0003
Vancouver
PLACZEK M, KOSELA M. Microscopic methods in analysis of submicron phospholipid dispersions. Acta Pharm. [Internet]. 2016 [pristupljeno 24.08.2019.];66(1):1-22. https://doi.org/10.1515/acph-2016-0003
IEEE
M. PLACZEK i M. KOSELA, "Microscopic methods in analysis of submicron phospholipid dispersions", Acta Pharmaceutica, vol.66, br. 1, str. 1-22, 2016. [Online]. https://doi.org/10.1515/acph-2016-0003

Sažetak
Microscopy belongs to the group of tests, used in pharmaceutical technology, that despite the lapse of time and the development of new analytical methods, still remain irreplaceable for the characterization of dispersed drug dosage forms (e.g. suspensions and emulsions). To obtain complete description of a specific drug formulation, such as parenteral colloidal products, a combination of different microscopic techniques sometimes is required. Electron microscopy methods are the most useful; however, even such basic methods as optical microscopy may be helpful for determination of some properties of a sample. The publication explicates the most popular microscopical techniques used nowadays for characterization of the morphology of nanoparticles suspended in pharmaceutical formulations; advantages and disadvantages of these methods are also discussed. Parenteral submicron formulations containing lecithin or a particular phospholipid were chosen as examples

Ključne riječi
optical microscopy; electron microscopy; AFM; phospholipid dispersions; parenteral drug delivery systems

Hrčak ID: 145327

URI
https://hrcak.srce.hr/145327

Posjeta: 1.412 *