Acta clinica Croatica, Vol. 40 No. 1, 2001.
Stručni rad
Collecting Duct Carcinoma of the Kidney: Report of Three Cases
Božo Krušlin
Ivana Glumbić
Ante Reljić
Hrvoje Čupić
Boris Ružić
Goran Štimac
Mladen Belicza
Sažetak
Collecting duct carcinoma or Bellini duct carcinoma is a highly malignant neoplasm that arises from the collecting duct epithelium of the kidney and accounts for approximately 1% of renal neoplasms. Collecting duct carcinoma generally pursues a more aggressive course than conventional renal cell carcinoma. Metastases to regional lymph nodes, bone, adrenal glands, lung, skin and meninges have been reported. During the 1998-2000 period, 161 patients underwent nephrectomy due to renal cell carcinoma at our hospital. The patients’ age ranged from 24 to 90 (mean 59.5) years. There were 50 female and 111 male patients. Collecting duct carcinoma was diagnosed in three (1.9%) male patients aged 79, 66 and 67 (mean age 71.0) years. The patients presented with hematuria associated with fever, weight loss, pain and palpable abdominal mass. On gross examination, the tumors were located in the medulla of the kidney and extended into the cortex and adjacent adipose tissue. Histologically, the tumors showed tubulopapillary, tubular or solid areas. Immunohistochemically, positive staining with cytokeratin, EMA and Ulex Europaeus agglutinin was observed. All patients had regional lymph node metastases, and two of them died within one month from surgery. The third patient was alive and without signs of recurrence six months from presentation.
Ključne riječi
Kidney neoplasms, pathology; Kidney neoplasms, diagnosis
Hrčak ID:
14844
URI
Datum izdavanja:
1.3.2001.
Posjeta: 3.348 *