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The role of androgens and estrogens in Hidradenitis Suppurativa – a Systematic Review

Peter Theut Riis ; University hospital Zealand, Roskilde, Derpartment of Dermatology
Hans Christian Ring
Lotte Themstrup
Gregor Borut Jemec

Puni tekst: engleski, PDF (159 KB) str. 239-239 preuzimanja: 574* citiraj
APA 6th Edition
Theut Riis, P., Ring, H.C., Themstrup, L. i Borut Jemec, G. (2016). The role of androgens and estrogens in Hidradenitis Suppurativa – a Systematic Review. Acta Dermatovenerologica Croatica, 24 (4), 239-239. Preuzeto s https://hrcak.srce.hr/173942
MLA 8th Edition
Theut Riis, Peter, et al. "The role of androgens and estrogens in Hidradenitis Suppurativa – a Systematic Review." Acta Dermatovenerologica Croatica, vol. 24, br. 4, 2016, str. 239-239. https://hrcak.srce.hr/173942. Citirano 17.10.2021.
Chicago 17th Edition
Theut Riis, Peter, Hans Christian Ring, Lotte Themstrup i Gregor Borut Jemec. "The role of androgens and estrogens in Hidradenitis Suppurativa – a Systematic Review." Acta Dermatovenerologica Croatica 24, br. 4 (2016): 239-239. https://hrcak.srce.hr/173942
Harvard
Theut Riis, P., et al. (2016). 'The role of androgens and estrogens in Hidradenitis Suppurativa – a Systematic Review', Acta Dermatovenerologica Croatica, 24(4), str. 239-239. Preuzeto s: https://hrcak.srce.hr/173942 (Datum pristupa: 17.10.2021.)
Vancouver
Theut Riis P, Ring HC, Themstrup L, Borut Jemec G. The role of androgens and estrogens in Hidradenitis Suppurativa – a Systematic Review. Acta Dermatovenerol Croat. [Internet]. 2016 [pristupljeno 17.10.2021.];24(4):239-239. Dostupno na: https://hrcak.srce.hr/173942
IEEE
P. Theut Riis, H.C. Ring, L. Themstrup i G. Borut Jemec, "The role of androgens and estrogens in Hidradenitis Suppurativa – a Systematic Review", Acta Dermatovenerologica Croatica, vol.24, br. 4, str. 239-239, 2016. [Online]. Dostupno na: https://hrcak.srce.hr/173942. [Citirano: 17.10.2021.]

Sažetak

Hidradenitis suppurativa (HS) is an inflammatory skin disease. Several observations imply that sex hormones may play a role in its pathogenesis. HS is more common in women, and the disease severity appears to vary in intensity according to the menstrual cycle. In addition, parallels have been drawn between HS and acne vulgaris, suggesting that sex hormones may play a role in the condition. The role of androgens and estrogens in HS has therefore been explored in numerous observational and some interventional studies; however, the studies have often reported conflicting results. This systematic review includes 59 unique articles and aims to give an overview of the available research. Articles containing information on natural variation, severity changes during menstruation and pregnancy, as well as articles on serum levels of hormones in patients with HS and the therapeutic options of hormonal manipulation therapy have all been included and are presented in this systematic review. Our results show that patients with HS do not seem to have increased levels of sex hormones and that their hormone levels lie within the normal range. While decreasing levels of progesterone and estrogen seem to coincide with disease flares in premenopausal women, the association is speculative and requires experimental confirmation. Antiandrogen treatment could be a valuable approach in treating HS, however randomized control trials are lacking.

Hrčak ID: 173942

URI
https://hrcak.srce.hr/173942

Posjeta: 839 *