hrcak mascot   Srce   HID

Stručni rad

RENAL DENERVATION AND RESISTANT HYPERTENSION: BACK TO THE FUTURE

INGRID PRKAČIN   ORCID icon orcid.org/0000-0002-5830-7131 ; University of Zagreb, School of Medicine, Merkur University Hospital, Department of Internal Medicine, and Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, Zagreb, Croatia
BORNA VRHOVEC ; University of Zagreb, School of Medicine, Merkur University Hospital, Department of Internal Medicine, Zagreb, Croatia
ANA LEGOVIĆ ; University of Zagreb, School of Medicine, Merkur University Hospital, Department of Internal Medicine, Zagreb, Croatia
VESNA ĐERMANOVIĆ DOBROTA ; University of Zagreb, School of Medicine, Merkur University Hospital, Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, Zagreb, Croatia
TOMISLAV BULUM ; University of Zagreb, School of Medicine, Merkur University Hospital, Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, Zagreb, Croatia
VINKO VIDJAK ; University of Zagreb, School of Medicine, Merkur University Hospital, Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, and Department of Radiology, Zagreb, Croatia

Puni tekst: engleski, pdf (206 KB) str. 41-44 preuzimanja: 79* citiraj
APA 6th Edition
PRKAČIN, I., VRHOVEC, B., LEGOVIĆ, A., ĐERMANOVIĆ DOBROTA, V., BULUM, T. i VIDJAK, V. (2016). RENAL DENERVATION AND RESISTANT HYPERTENSION: BACK TO THE FUTURE. Acta medica Croatica, 70 (Suplement 2), 41-44. Preuzeto s https://hrcak.srce.hr/180121
MLA 8th Edition
PRKAČIN, INGRID, et al. "RENAL DENERVATION AND RESISTANT HYPERTENSION: BACK TO THE FUTURE." Acta medica Croatica, vol. 70, br. Suplement 2, 2016, str. 41-44. https://hrcak.srce.hr/180121. Citirano 21.10.2019.
Chicago 17th Edition
PRKAČIN, INGRID, BORNA VRHOVEC, ANA LEGOVIĆ, VESNA ĐERMANOVIĆ DOBROTA, TOMISLAV BULUM i VINKO VIDJAK. "RENAL DENERVATION AND RESISTANT HYPERTENSION: BACK TO THE FUTURE." Acta medica Croatica 70, br. Suplement 2 (2016): 41-44. https://hrcak.srce.hr/180121
Harvard
PRKAČIN, I., et al. (2016). 'RENAL DENERVATION AND RESISTANT HYPERTENSION: BACK TO THE FUTURE', Acta medica Croatica, 70(Suplement 2), str. 41-44. Preuzeto s: https://hrcak.srce.hr/180121 (Datum pristupa: 21.10.2019.)
Vancouver
PRKAČIN I, VRHOVEC B, LEGOVIĆ A, ĐERMANOVIĆ DOBROTA V, BULUM T, VIDJAK V. RENAL DENERVATION AND RESISTANT HYPERTENSION: BACK TO THE FUTURE. Acta medica Croatica [Internet]. 2016 [pristupljeno 21.10.2019.];70(Suplement 2):41-44. Dostupno na: https://hrcak.srce.hr/180121
IEEE
I. PRKAČIN, B. VRHOVEC, A. LEGOVIĆ, V. ĐERMANOVIĆ DOBROTA, T. BULUM i V. VIDJAK, "RENAL DENERVATION AND RESISTANT HYPERTENSION: BACK TO THE FUTURE", Acta medica Croatica, vol.70, br. Suplement 2, str. 41-44, 2016. [Online]. Dostupno na: https://hrcak.srce.hr/180121. [Citirano: 21.10.2019.]

Sažetak
Renal sympathetic denervation (RDN) with radiofrequency (RF) is being used to treat resistant hypertension in seven non-responder patients (62±6 years for age, 5F/2M) despite treatment with >4 different antihypertensive drugs in optimal doses. Prior to diagnosing a patient as having resistant hypertension, we document adherence and exclude white-coat hypertension, inaccurate measurement of blood pressure and secondary causes. Office blood pressure (BP) measurements at 1, 3, 6, 12 and 18 months follow-up visits were compared to baseline. We used STATISTICA 10, 2011 software (Stat Soft Inc., Tulsa, OK, USA). Values are mean SD and considered statistically significant if P <0.001. At baseline, values were 184±21 and 106±26 mmHg for systolic (SBP) and diastolic (DBP), 6.7±1 for number of antihypertensive drug classes. One, 3, 6, 12 and 18 months after RDN, office SBP values were significantly lower (144±13 mmHg, 140±17, 141±15, 139±12 and 135±11 mmHg; P <0.001), with no significant reduction in DBP values at 1, 3, 6, 12 and 18 months after RDN (81±6, 82±9, 79±9, 78±6, and 76±7 mmHg). The number of antihypertensive drug classes before and 6, 12, 18 months after RDN were evaluated. Six months after RDN the number of antihypertensive drug classes required was 6.5±1, after 12 and 18 months was 5.5±1 and 4.5±1. During RDA no complications occurred (the pain during the procedure was well tolerated) and the renal function remained stabile. Renal sympathetic denervation is being a concomitant treatment of drug-resistant hypertension (rHT). The sustained reduction of SBP was observed after the RDN. Patients have benefit the most from procedure after 6-12 months. Further meta-analysis will evaluate the importance of new devices for less pain treatment of RDN.

Ključne riječi
resistant hypertension; renal sympathetic denervation

Hrčak ID: 180121

URI
https://hrcak.srce.hr/180121

[hrvatski]

Posjeta: 187 *