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Medicinski vjesnik, Vol.30 No.(1-2) Prosinac 1998.

Stručni rad

Pre-symptomatic diagnostics of medullary thyroid carcinoma using r-DNA methods

Koraljka Gall-Trošelj

Puni tekst: engleski, pdf (2 MB) str. 23-27 preuzimanja: 9* citiraj
APA
Gall-Trošelj, K. (1998). Pre-symptomatic diagnostics of medullary thyroid carcinoma using r-DNA methods. Medicinski vjesnik, 30((1-2)), 23-27. Preuzeto s https://hrcak.srce.hr/192071
Puni tekst: hrvatski, pdf (2 MB) str. 23-27 preuzimanja: 13* citiraj
APA
Gall-Trošelj, K. (1998). Presimptomatsko otkrivanje medularnog karcinoma štitnjače metodama rekombinacijske tehnologije DNA. Medicinski vjesnik, 30((1-2)), 23-27. Preuzeto s https://hrcak.srce.hr/192071

Sažetak
The distinction of sporadic from inherited medullary thyroid carcinomas (MTCs) is of clinical importance because of the differences in prognosis and the need for family screening for genetic counselling required in the latter. Germline mutations in the ret proto-oncogene are associated with multiple endocrine neoplasia type 2. Somatic point mutations in the same gene are identified in a subset of sporadically occurring MTCs. The methods of molecular medicine are suitable to distinguish heritable from non-heritable MTCs and identify asymptomatic individuals at risk.

Ključne riječi
medullary thyroid carcinoma; DNA analysis; pre-symptomatic diagnostics

Hrčak ID: 192071

URI
https://hrcak.srce.hr/192071

[hrvatski]

Posjeta: 36 *