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Medicinski vjesnik, Vol.30 No.(1-2) Prosinac 1998.

Stručni rad

The effects of suppressive therapy of difuse euthyroid goitre with levothyroxine (comparation on effects in younger and middle-aged patients)

Ivica Mihaljević
Ivan Karner
Juraj Smoje

Puni tekst: engleski, pdf (1 MB) str. 29-31 preuzimanja: 12* citiraj
APA 6th Edition
Mihaljević, I., Karner, I. i Smoje, J. (1998). The effects of suppressive therapy of difuse euthyroid goitre with levothyroxine (comparation on effects in younger and middle-aged patients). Medicinski vjesnik, 30 ((1-2)), 29-31. Preuzeto s https://hrcak.srce.hr/192075
MLA 8th Edition
Mihaljević, Ivica, et al. "The effects of suppressive therapy of difuse euthyroid goitre with levothyroxine (comparation on effects in younger and middle-aged patients)." Medicinski vjesnik, vol. 30, br. (1-2), 1998, str. 29-31. https://hrcak.srce.hr/192075. Citirano 23.10.2018.
Chicago 17th Edition
Mihaljević, Ivica, Ivan Karner i Juraj Smoje. "The effects of suppressive therapy of difuse euthyroid goitre with levothyroxine (comparation on effects in younger and middle-aged patients)." Medicinski vjesnik 30, br. (1-2) (1998): 29-31. https://hrcak.srce.hr/192075
Harvard
Mihaljević, I., Karner, I., i Smoje, J. (1998). 'The effects of suppressive therapy of difuse euthyroid goitre with levothyroxine (comparation on effects in younger and middle-aged patients)', Medicinski vjesnik, 30((1-2)), str. 29-31. Preuzeto s: https://hrcak.srce.hr/192075 (Datum pristupa: 23.10.2018.)
Vancouver
Mihaljević I, Karner I, Smoje J. The effects of suppressive therapy of difuse euthyroid goitre with levothyroxine (comparation on effects in younger and middle-aged patients). Medicinski vjesnik [Internet]. 01.12.1998. [pristupljeno 23.10.2018.];30((1-2)):29-31. Dostupno na: https://hrcak.srce.hr/192075
IEEE
I. Mihaljević, I. Karner i J. Smoje, "The effects of suppressive therapy of difuse euthyroid goitre with levothyroxine (comparation on effects in younger and middle-aged patients)", Medicinski vjesnik, vol.30, br. (1-2), str. 29-31, prosinac 1998. [Online]. Dostupno na: https://hrcak.srce.hr/192075. [Citirano: 23.10.2018.]
Puni tekst: hrvatski, pdf (1 MB) str. 29-31 preuzimanja: 13* citiraj
APA 6th Edition
Mihaljević, I., Karner, I. i Smoje, J. (1998). Učinci supresijske terapije difuznih eutireoidnih struma preparatima tiroksina (Komparacija učinaka u oboljelih mlađe i srednje životne dobi). Medicinski vjesnik, 30 ((1-2)), 29-31. Preuzeto s https://hrcak.srce.hr/192075
MLA 8th Edition
Mihaljević, Ivica, et al. "Učinci supresijske terapije difuznih eutireoidnih struma preparatima tiroksina (Komparacija učinaka u oboljelih mlađe i srednje životne dobi)." Medicinski vjesnik, vol. 30, br. (1-2), 1998, str. 29-31. https://hrcak.srce.hr/192075. Citirano 23.10.2018.
Chicago 17th Edition
Mihaljević, Ivica, Ivan Karner i Juraj Smoje. "Učinci supresijske terapije difuznih eutireoidnih struma preparatima tiroksina (Komparacija učinaka u oboljelih mlađe i srednje životne dobi)." Medicinski vjesnik 30, br. (1-2) (1998): 29-31. https://hrcak.srce.hr/192075
Harvard
Mihaljević, I., Karner, I., i Smoje, J. (1998). 'Učinci supresijske terapije difuznih eutireoidnih struma preparatima tiroksina (Komparacija učinaka u oboljelih mlađe i srednje životne dobi)', Medicinski vjesnik, 30((1-2)), str. 29-31. Preuzeto s: https://hrcak.srce.hr/192075 (Datum pristupa: 23.10.2018.)
Vancouver
Mihaljević I, Karner I, Smoje J. Učinci supresijske terapije difuznih eutireoidnih struma preparatima tiroksina (Komparacija učinaka u oboljelih mlađe i srednje životne dobi). Medicinski vjesnik [Internet]. 01.12.1998. [pristupljeno 23.10.2018.];30((1-2)):29-31. Dostupno na: https://hrcak.srce.hr/192075
IEEE
I. Mihaljević, I. Karner i J. Smoje, "Učinci supresijske terapije difuznih eutireoidnih struma preparatima tiroksina (Komparacija učinaka u oboljelih mlađe i srednje životne dobi)", Medicinski vjesnik, vol.30, br. (1-2), str. 29-31, prosinac 1998. [Online]. Dostupno na: https://hrcak.srce.hr/192075. [Citirano: 23.10.2018.]

Sažetak
In a prospective study 67 patients with diffuse euthyroid goitre, between 17 and 21 years old (group I, n=28) and between 33 and 45 years old (group II, n=39), were treated for one year with 100 levothyroxine daily, have been evaluated effects of supressive therapy measured by sonography and palpation. After 3, 6, 9 and 12 months the reduction of the goitre volume was significantly different from the initial volume in both groups. In both forms of treatment maximum volume decrease was already seen within the first six months. After treatment for 6 months the mean decrease of thyroid volumes was 19.2% in group I and 28.6% in group II. After treatment for 12 months the mean decrease of thyroid volumes was 23.5% in group I and 32.3% in group II compared to the initial volume. In group I after 1 month (in group II after 2 months) a more significant increase of T4 and of fT4 values within the normal range was observed immediately after supressive therapy. There were no changes of the T3 and fT3 values. In both groups it has been found out that in the first 6 months and after 1 year therapy with levothyroxine exist a comparable efficiency for the reduction of goiters with statistically significant differences in favour group II.

Ključne riječi
diffuse euthyroid goitre; suppressive therapy; levothyroxine

Hrčak ID: 192075

URI
https://hrcak.srce.hr/192075

[hrvatski]

Posjeta: 41 *