Interactions of a-Chymotrypsinogen A with Some Alkylureas
S. Lapanje
; Department of Chemistry and Chemical Technology, Edvard Kardelj University, Ljubljana, Yugoslavia
M. Simič
; Department of Chemistry and Chemical Technology, Edvard Kardelj University, Ljubljana, Yugoslavia
A. Pavlič
; Department of Chemistry and Chemical Technology, Edvard Kardelj University, Ljubljana, Yugoslavia
APA 6th Edition Lapanje, S., Simič, M. i Pavlič, A. (1981). Interactions of a-Chymotrypsinogen A with Some Alkylureas. Croatica Chemica Acta, 54 (4), 481-488. Preuzeto s https://hrcak.srce.hr/194313
MLA 8th Edition Lapanje, S., et al. "Interactions of a-Chymotrypsinogen A with Some Alkylureas." Croatica Chemica Acta, vol. 54, br. 4, 1981, str. 481-488. https://hrcak.srce.hr/194313. Citirano 04.03.2021.
Chicago 17th Edition Lapanje, S., M. Simič i A. Pavlič. "Interactions of a-Chymotrypsinogen A with Some Alkylureas." Croatica Chemica Acta 54, br. 4 (1981): 481-488. https://hrcak.srce.hr/194313
Harvard Lapanje, S., Simič, M., i Pavlič, A. (1981). 'Interactions of a-Chymotrypsinogen A with Some Alkylureas', Croatica Chemica Acta, 54(4), str. 481-488. Preuzeto s: https://hrcak.srce.hr/194313 (Datum pristupa: 04.03.2021.)
Vancouver Lapanje S, Simič M, Pavlič A. Interactions of a-Chymotrypsinogen A with Some Alkylureas. Croatica Chemica Acta [Internet]. 1981 [pristupljeno 04.03.2021.];54(4):481-488. Dostupno na: https://hrcak.srce.hr/194313
IEEE S. Lapanje, M. Simič i A. Pavlič, "Interactions of a-Chymotrypsinogen A with Some Alkylureas", Croatica Chemica Acta, vol.54, br. 4, str. 481-488, 1981. [Online]. Dostupno na: https://hrcak.srce.hr/194313. [Citirano: 04.03.2021.]
Sažetak The interactions of a-chymotrypsinogen A with urea, methyl-,
N,N'-dimethyl-, ethyl-, N,N'-diethyl-, and propylurea were studied
by means of calorimetry and circular dichroism. It has been found
that the enthalpies of interaction of the alkylureas, with the
exception of methylurea, with a-chymotrypsinogen A are distinctly
from those of urea. Thus the transfer of the protein from water to
aqueous urea and methylurea solutions is accompanied by release
of heat, · i.e., the overall reaction is exothermic, whereas the
transfer of the same protein to solutions of other alkylureas is
characterized by consumption of heat, i.e., the overall reaction
is endothermic. By examining the far UV CD spectra it can also
be concluded that the alkylureas are clearly less efficient denaturants
than urea. The difference in behavior reflects the presence
of the hydrophobic moiety in the urea molecule.