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Review article

Current knowledge about prostatic cancer a proposal for a common therapy protocol

Rudjer Novak
Antun Tucak
Krešimir Glavina
Domagoj Glavina

Fulltext: english, pdf (4 MB) pages 31-38 downloads: 50* cite
APA 6th Edition
Novak, R., Tucak, A., Glavina, K. & Glavina, D. (1991). Current knowledge about prostatic cancer a proposal for a common therapy protocol. Medicinski vjesnik, 23 ((1-2)), 31-38. Retrieved from https://hrcak.srce.hr/195821
MLA 8th Edition
Novak, Rudjer, et al. "Current knowledge about prostatic cancer a proposal for a common therapy protocol." Medicinski vjesnik, vol. 23, no. (1-2), 1991, pp. 31-38. https://hrcak.srce.hr/195821. Accessed 25 Jul. 2021.
Chicago 17th Edition
Novak, Rudjer, Antun Tucak, Krešimir Glavina and Domagoj Glavina. "Current knowledge about prostatic cancer a proposal for a common therapy protocol." Medicinski vjesnik 23, no. (1-2) (1991): 31-38. https://hrcak.srce.hr/195821
Harvard
Novak, R., et al. (1991). 'Current knowledge about prostatic cancer a proposal for a common therapy protocol', Medicinski vjesnik, 23((1-2)), pp. 31-38. Available at: https://hrcak.srce.hr/195821 (Accessed 25 July 2021)
Vancouver
Novak R, Tucak A, Glavina K, Glavina D. Current knowledge about prostatic cancer a proposal for a common therapy protocol. Medicinski vjesnik [Internet]. 1991 [cited 2021 July 25];23((1-2)):31-38. Available from: https://hrcak.srce.hr/195821
IEEE
R. Novak, A. Tucak, K. Glavina and D. Glavina, "Current knowledge about prostatic cancer a proposal for a common therapy protocol", Medicinski vjesnik, vol.23, no. (1-2), pp. 31-38, 1991. [Online]. Available: https://hrcak.srce.hr/195821. [Accessed: 25 July 2021]
Fulltext: croatian, pdf (4 MB) pages 31-38 downloads: 153* cite
APA 6th Edition
Novak, R., Tucak, A., Glavina, K. & Glavina, D. (1991). Današnje spoznaje o karcinomu prostate - prijedlog za zajednički koncept terapije. Medicinski vjesnik, 23 ((1-2)), 31-38. Retrieved from https://hrcak.srce.hr/195821
MLA 8th Edition
Novak, Rudjer, et al. "Današnje spoznaje o karcinomu prostate - prijedlog za zajednički koncept terapije." Medicinski vjesnik, vol. 23, no. (1-2), 1991, pp. 31-38. https://hrcak.srce.hr/195821. Accessed 25 Jul. 2021.
Chicago 17th Edition
Novak, Rudjer, Antun Tucak, Krešimir Glavina and Domagoj Glavina. "Današnje spoznaje o karcinomu prostate - prijedlog za zajednički koncept terapije." Medicinski vjesnik 23, no. (1-2) (1991): 31-38. https://hrcak.srce.hr/195821
Harvard
Novak, R., et al. (1991). 'Današnje spoznaje o karcinomu prostate - prijedlog za zajednički koncept terapije', Medicinski vjesnik, 23((1-2)), pp. 31-38. Available at: https://hrcak.srce.hr/195821 (Accessed 25 July 2021)
Vancouver
Novak R, Tucak A, Glavina K, Glavina D. Današnje spoznaje o karcinomu prostate - prijedlog za zajednički koncept terapije. Medicinski vjesnik [Internet]. 1991 [cited 2021 July 25];23((1-2)):31-38. Available from: https://hrcak.srce.hr/195821
IEEE
R. Novak, A. Tucak, K. Glavina and D. Glavina, "Današnje spoznaje o karcinomu prostate - prijedlog za zajednički koncept terapije", Medicinski vjesnik, vol.23, no. (1-2), pp. 31-38, 1991. [Online]. Available: https://hrcak.srce.hr/195821. [Accessed: 25 July 2021]

Abstracts
General frequency of prostatic cancer (including incidental and undetected) outnumbers clinical prostatic cancer, although this one is by far the most frequent cancer of man. Current diagnosis of clinical prostatic cancer is based on digital examination, rectal ultrasound, serum prostatic specific antigen level and transrectal biopsy. Modern classification has to separate localized from advanced and disseminated disease. A high percent age of prostatic cancer is inactive disease whose mortality does not outnumber the man lethality without cancer. Today, we have some concrete factors indicating the disease aggressive potential, e.g. regional lymph node growth, high PSA and PAP levels, primary tumor size, high grading and nuclear aneuploidy. With them, the cases requiring therapy can be differentiated from those with inactive cancer. Localized aggressive prostatic cancer with general conditions for operation fulfilled indicates radical prostatectomy. The advanced and disseminated disease is an indication for paliative therapy, which is based on complete androgen deprivation. This is achieved in the first phase of therapy with orchydectomy + GnLH analogues + antiandrogens. The next therapeutic phase (after new disease progression ) consists of phosphorilized stilbens, such as Estracyt and Honvan. The final, exclusively symptomatic therapy should be preceded by chemotherapy.

Keywords
prostatic cancer

Hrčak ID: 195821

URI
https://hrcak.srce.hr/195821

[croatian]

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