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https://doi.org/10.26582/k.50.2.18

Male sex hormones response after a month-long himalayas trek in relation to hemoglobin oxygen saturation

Lana Ružić ; Dpt. Sport and Exercise Medicine, Faculty of Kinesiology, University of Zagreb, Croatia
Maja Cigrovski Berković ; Department for Endocrinology, Diabetes and Metabolism, University Hospital Centre “Sestre milosrdnice”, Zagreb, Croatia
Hrvoje Starčević ; Private practice Dr. Starcevic, Zagreb, Croatia
Dražen Lovrić ; Special Hospital for Orthopaedic Surgery Akromion, Krapinske Toplice, Croatia
Branka R. Matković ; Dpt. Sport and Exercise Medicine, Faculty of Kinesiology, University of Zagreb, Croatia

Puni tekst: engleski, pdf (963 KB) str. 157-164 preuzimanja: 461* citiraj
APA 6th Edition
Ružić, L., Cigrovski Berković, M., Starčević, H., Lovrić, D. i R. Matković, B. (2018). Male sex hormones response after a month-long himalayas trek in relation to hemoglobin oxygen saturation. Kinesiology, 50. (2.), 157-164. https://doi.org/10.26582/k.50.2.18
MLA 8th Edition
Ružić, Lana, et al. "Male sex hormones response after a month-long himalayas trek in relation to hemoglobin oxygen saturation." Kinesiology, vol. 50., br. 2., 2018, str. 157-164. https://doi.org/10.26582/k.50.2.18. Citirano 26.09.2021.
Chicago 17th Edition
Ružić, Lana, Maja Cigrovski Berković, Hrvoje Starčević, Dražen Lovrić i Branka R. Matković. "Male sex hormones response after a month-long himalayas trek in relation to hemoglobin oxygen saturation." Kinesiology 50., br. 2. (2018): 157-164. https://doi.org/10.26582/k.50.2.18
Harvard
Ružić, L., et al. (2018). 'Male sex hormones response after a month-long himalayas trek in relation to hemoglobin oxygen saturation', Kinesiology, 50.(2.), str. 157-164. https://doi.org/10.26582/k.50.2.18
Vancouver
Ružić L, Cigrovski Berković M, Starčević H, Lovrić D, R. Matković B. Male sex hormones response after a month-long himalayas trek in relation to hemoglobin oxygen saturation. Kinesiology [Internet]. 2018 [pristupljeno 26.09.2021.];50.(2.):157-164. https://doi.org/10.26582/k.50.2.18
IEEE
L. Ružić, M. Cigrovski Berković, H. Starčević, D. Lovrić i B. R. Matković, "Male sex hormones response after a month-long himalayas trek in relation to hemoglobin oxygen saturation", Kinesiology, vol.50., br. 2., str. 157-164, 2018. [Online]. https://doi.org/10.26582/k.50.2.18

Sažetak
High-altitude tourism is becoming increasingly popular among non-athletic population, but its potential impact on health is often neglected. This study investigated the changes in male sex hormones after the trek at altitudes between 1400 m and 6476 m. Seventeen recreational lowland men (age 48±11 years) participated in a 26-day Himalayan trek, with the highest point reached being Mera Peak. The initial measurements were performed 10 days before departure and included blood tests (total testosterone, sex hormone-binding globulin – SHBG, dehydroepiandrosterone sulfate – DHEA-S, follicle stimulating hormone – FSH, and luteinizing hormone – LH) and ergometry on a treadmill. The final measurements were done 24 h after the return to 122 m (four days after reaching the altitude of 4300 m, and eight days after the altitude of 6476 m). During the tour, SpO2 and heart rate were measured 21 times. An increase in SHBG (42.6±10.6 to 50.7±12.0 nmol·L-1; p=.011), and subsequent decrease in calculated free testosterone (1.8±0.3 to 1.6±0.3%; p=.003) were observed. There was a significant correlation between the relative testosterone decrease and SHBG with mean SpO2 (Spearman R=-0.64 and 0.41, respectively). LH and FSH increased significantly (FSH Median/ IQR before=3.9/3.1-5.4 and after 4.6/4.0-7.1 IU·L-1; p=.001 and LH Median/IQR before=4.8/3.1-5.2 and after 5.9/4.9-9.3 IU·L-1; p=.008). The changes in LH and FSH did not correlate with SpO2, whereas the physical fitness levels (expressed in MET) did. The pituitary-adrenal-gonadal axis was affected by the altitude trek (involving physical exertion and hypoxia in combination), but the origin, duration and impact of changes in various aspects of men’s health should be further investigated.

Ključne riječi
altitude; gonadotropins; testosterone; hypoxia

Hrčak ID: 212540

URI
https://hrcak.srce.hr/212540

Posjeta: 739 *