Pregledni rad
https://doi.org/10.20471/LO.2018.46.02-03.13
Management of young women with early breast cancer – focus on fertility preservation
Petra Vuković
; Division of Radiotherapy and Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Jelena Raguž
; Division of Radiotherapy and Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Lidija Beketić-Orešković
; Division of Radiotherapy and Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; Department of Clinical Oncology, School of Medicine, University of Zagreb, Zagreb, Croatia
Sažetak
Management of young women with breast cancer is complex and has several particularities, one of which is fertility preservation, a very important quality of life issue for young breast cancer survivors. Chemotherapy can be gonadotoxic and significantly reduce woman`s reproductive potential and cause premature ovarian insufficiency while endocrine therapy requires a delay of pregnancy and indirectly affects fertility. Therefore every woman of reproductive age diagnosed with breast cancer should be informed about potential gonadotoxic effect of cancer treatment, the risk of premature ovarian insufficiency and associated symptoms, available fertility preservation methods, delay of cancer treatment and chances of subsequent pregnancy. If interested in fertility preservation breast cancer patients should be referred as early as possible to a reproductive specialist to further discuss the risk of infertility and available fertility preservation options. Currently established methods for fertility preservation are embryo and oocyte cryopreservation, while ovarian tissue cryopreservation, cryopreservation of immature oocytes and ovarian suppression with gonadotropin-releasing hormone agonists are still considered experimental.
The aim of this review is to highlight the importance of fertility preservation as an important quality of life issue for young breast cancer survivors.
Ključne riječi
breast cancer; fertility preservation; pregnancy; quality of life
Hrčak ID:
217798
URI
Datum izdavanja:
29.1.2019.
Posjeta: 1.304 *