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Comparing the efficacy of mesotherapy to topical minoxidil in the treatment of female pattern hair loss using ultrasound biomicroscopy: A randomized controlled trial

Nahla Hunter ; Dermatology Department, Faculty of Medicine, Cairo University, Egypt
Khadiga Sayed ; Dermatology Department, Faculty of Medicine, Cairo University, Egypt
Rania Abdel Hay   ORCID icon orcid.org/0000-0002-3280-0796 ; Cairo University, Egypt
Riham Allam   ORCID icon orcid.org/0000-0002-1857-1923 ; Ophthalmology Department, Faculty of Medicine, Cairo University, Egypt
Nada Hussein ; Dermatology Department, Faculty of Medicine, Cairo University, Egypt

Puni tekst: engleski, PDF (203 KB) str. 1-1 preuzimanja: 576* citiraj
APA 6th Edition
Hunter, N., Sayed, K., Abdel Hay, R., Allam, R. i Hussein, N. (2019). Comparing the efficacy of mesotherapy to topical minoxidil in the treatment of female pattern hair loss using ultrasound biomicroscopy: A randomized controlled trial. Acta Dermatovenerologica Croatica, 27 (1), 1-1. Preuzeto s https://hrcak.srce.hr/219580
MLA 8th Edition
Hunter, Nahla, et al. "Comparing the efficacy of mesotherapy to topical minoxidil in the treatment of female pattern hair loss using ultrasound biomicroscopy: A randomized controlled trial." Acta Dermatovenerologica Croatica, vol. 27, br. 1, 2019, str. 1-1. https://hrcak.srce.hr/219580. Citirano 27.10.2021.
Chicago 17th Edition
Hunter, Nahla, Khadiga Sayed, Rania Abdel Hay, Riham Allam i Nada Hussein. "Comparing the efficacy of mesotherapy to topical minoxidil in the treatment of female pattern hair loss using ultrasound biomicroscopy: A randomized controlled trial." Acta Dermatovenerologica Croatica 27, br. 1 (2019): 1-1. https://hrcak.srce.hr/219580
Harvard
Hunter, N., et al. (2019). 'Comparing the efficacy of mesotherapy to topical minoxidil in the treatment of female pattern hair loss using ultrasound biomicroscopy: A randomized controlled trial', Acta Dermatovenerologica Croatica, 27(1), str. 1-1. Preuzeto s: https://hrcak.srce.hr/219580 (Datum pristupa: 27.10.2021.)
Vancouver
Hunter N, Sayed K, Abdel Hay R, Allam R, Hussein N. Comparing the efficacy of mesotherapy to topical minoxidil in the treatment of female pattern hair loss using ultrasound biomicroscopy: A randomized controlled trial. Acta Dermatovenerol Croat. [Internet]. 2019 [pristupljeno 27.10.2021.];27(1):1-1. Dostupno na: https://hrcak.srce.hr/219580
IEEE
N. Hunter, K. Sayed, R. Abdel Hay, R. Allam i N. Hussein, "Comparing the efficacy of mesotherapy to topical minoxidil in the treatment of female pattern hair loss using ultrasound biomicroscopy: A randomized controlled trial", Acta Dermatovenerologica Croatica, vol.27, br. 1, str. 1-1, 2019. [Online]. Dostupno na: https://hrcak.srce.hr/219580. [Citirano: 27.10.2021.]

Sažetak

The efficacy of mesotherapy in the treatment of female pattern hair loss (FPHL) has not yet been evaluated. Aim of the study was to compare the initial efficacy and safety of mesotherapy containing nutritional supplements to topical minoxidil 5% solution in FPHL. 30 patients with FPHL were randomly classified into two equal groups: Group A applied minoxidil 5% lotion twice daily; Group B was injected with mesotherapy once weekly. For both groups ultrasound biomicroscopy (UBM) was performed before and at the end of the 12th week of treatment. After treatment, no significant difference was found between both groups with regard to either improvement of hair density and hair loss (P=0.27 and 0.056, respectively), nor the degree of improvement of Ludwig’s classification as assessed by the investigator (P=0.210). A significant difference was observed between both groups (P=0.001) with the highest degree of satisfaction in the mesotherapy group. In group A, no significant difference was found in the number of hair follicles or the diameter of the largest hair follicle (P=0.244 and 0.925, respectively). In group B, a significant difference was found in the number of hair follicles (P=0.001), with no significant difference in the diameter of the largest hair follicle (P=0.105). The mesotherapy group showed more improvement with regard to the increase in the number of the hair follicles after treatment (P=0.007). Limitation of the study is small sample size, and relatively short duration of treatment.

Mesotherapy, containing nutritional supplements only, is an effective, more acceptable to patients, and more tolerable modality compared with topical minoxidil in the treatment of FPHL.

 

Ključne riječi
Hair fall; Mesotherapy; Minoxidil; Ultrasound biomicroscopy

Hrčak ID: 219580

URI
https://hrcak.srce.hr/219580

Posjeta: 1.108 *