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An unknown horse disease appeared in Mraclin 80 years ago - what caused “Mraclin horse disease“?

Željko Cvetnić ; Veterinarski zavod Križevci, Hrvatski veterinarski institut, Zagreb, Hrvatska
Tomislav Sukalić ; Veterinarski zavod Križevci, Hrvatski veterinarski institut, Zagreb, Hrvatska
Vladimir Savić ; Centar za peradarstvo, Hrvatski veterinarski institut, Zagreb, Hrvatska
Željko Grabarević ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska

Puni tekst: hrvatski, pdf (670 KB) str. 201-210 preuzimanja: 85* citiraj
APA 6th Edition
Cvetnić, Ž., Sukalić, T., Savić, V. i Grabarević, Ž. (2019). Nepoznata bolest konja pojavila se u Mraclinu prije 80 godina - što je uzrok “mraclinske bolesti konja”? . Veterinarska stanica, 50 (3), 201-210. Preuzeto s https://hrcak.srce.hr/223827
MLA 8th Edition
Cvetnić, Željko, et al. "Nepoznata bolest konja pojavila se u Mraclinu prije 80 godina - što je uzrok “mraclinske bolesti konja”? ." Veterinarska stanica, vol. 50, br. 3, 2019, str. 201-210. https://hrcak.srce.hr/223827. Citirano 12.07.2020.
Chicago 17th Edition
Cvetnić, Željko, Tomislav Sukalić, Vladimir Savić i Željko Grabarević. "Nepoznata bolest konja pojavila se u Mraclinu prije 80 godina - što je uzrok “mraclinske bolesti konja”? ." Veterinarska stanica 50, br. 3 (2019): 201-210. https://hrcak.srce.hr/223827
Harvard
Cvetnić, Ž., et al. (2019). 'Nepoznata bolest konja pojavila se u Mraclinu prije 80 godina - što je uzrok “mraclinske bolesti konja”? ', Veterinarska stanica, 50(3), str. 201-210. Preuzeto s: https://hrcak.srce.hr/223827 (Datum pristupa: 12.07.2020.)
Vancouver
Cvetnić Ž, Sukalić T, Savić V, Grabarević Ž. Nepoznata bolest konja pojavila se u Mraclinu prije 80 godina - što je uzrok “mraclinske bolesti konja”? . Veterinarska stanica [Internet]. 2019 [pristupljeno 12.07.2020.];50(3):201-210. Dostupno na: https://hrcak.srce.hr/223827
IEEE
Ž. Cvetnić, T. Sukalić, V. Savić i Ž. Grabarević, "Nepoznata bolest konja pojavila se u Mraclinu prije 80 godina - što je uzrok “mraclinske bolesti konja”? ", Veterinarska stanica, vol.50, br. 3, str. 201-210, 2019. [Online]. Dostupno na: https://hrcak.srce.hr/223827. [Citirano: 12.07.2020.]

Sažetak
An acute neurological disease of horses appeared sporadically in September and October of 1938 in the villages of Rakarje, Buševec and Kurilovec in the Turopolje area, and as a limited epizootic event in Mraclin. The disease was named “Mraclin Horse Disease” (MHD). Of the 442 horses in the village, 200 came down with clinical signs and were treated, and 25 perished. All the affected horses had virtually identical acute neurological symptoms. The cause of the disease has not yet been proven, but the great similarity between the clinical signs of MHD with encephalomyelitis caused by the West Nile virus (WNV), suggested that WNV may have caused MHD in 1938. However, analysis of the pathological and pathohistological findings of horses that perished from MHD indicated massive necrosis of the liver caused by unknown toxin as the main cause of death. Neurological symptoms are a consequence of hepatic encephalopathy, and bleeding and icterus are obvious consequences of liver dysfunction. It can therefore be concluded that one of the possible causes of death was intoxication. This conclusion is based on the pathological findings of 1938, found in the archives of the Department of Pathology, Faculty of Veterinary Medicine, University of Zagreb. Another question that arises is what caused the poisoning of these horses? Differential diagnosis is difficult, but it is not impossible to exclude viral pathogens such as WNV, which would certainly help to detect the causative agent of MHD in 1938.

Ključne riječi
Mraclin; horse disease; Western Nile virus; intoxication

Hrčak ID: 223827

URI
https://hrcak.srce.hr/223827

[hrvatski]

Posjeta: 141 *