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Croatica Chemica Acta, Vol. 92 No. 2, 2019.

Pregledni rad
https://doi.org/10.5562/cca3556

Advances in Desmuramyl Peptide Research

Rosana Ribić   ORCID icon orcid.org/0000-0001-7611-538X ; University North, University Center Varaždin, Jurja Križanića 31b, HR-42000 Varaždin, Croatia
Marija Paurević ; Josip Juraj Strossmayer University of Osijek, Department of Chemistry, Ulica cara Hadrijana 8/A, HR-31000 Osijek, Croatia
Srđanka Tomić ; University of Zagreb, Faculty of Science, Department of Chemistry, Horvatovac 102a, HR-10000 Zagreb, Croatia

Puni tekst: engleski, pdf (2 MB) str. 153-161 preuzimanja: 251* citiraj
APA 6th Edition
Ribić, R., Paurević, M. i Tomić, S. (2019). Advances in Desmuramyl Peptide Research. Croatica Chemica Acta, 92 (2), 153-161. https://doi.org/10.5562/cca3556
MLA 8th Edition
Ribić, Rosana, et al. "Advances in Desmuramyl Peptide Research." Croatica Chemica Acta, vol. 92, br. 2, 2019, str. 153-161. https://doi.org/10.5562/cca3556. Citirano 22.04.2021.
Chicago 17th Edition
Ribić, Rosana, Marija Paurević i Srđanka Tomić. "Advances in Desmuramyl Peptide Research." Croatica Chemica Acta 92, br. 2 (2019): 153-161. https://doi.org/10.5562/cca3556
Harvard
Ribić, R., Paurević, M., i Tomić, S. (2019). 'Advances in Desmuramyl Peptide Research', Croatica Chemica Acta, 92(2), str. 153-161. https://doi.org/10.5562/cca3556
Vancouver
Ribić R, Paurević M, Tomić S. Advances in Desmuramyl Peptide Research. Croatica Chemica Acta [Internet]. 2019 [pristupljeno 22.04.2021.];92(2):153-161. https://doi.org/10.5562/cca3556
IEEE
R. Ribić, M. Paurević i S. Tomić, "Advances in Desmuramyl Peptide Research", Croatica Chemica Acta, vol.92, br. 2, str. 153-161, 2019. [Online]. https://doi.org/10.5562/cca3556

Sažetak
Immune adjuvants are added to vaccines in order to enhance the immune response to an antigen. Muramyl dipeptide,
N-acetylmuramyl-L-alanyl-D-isoglutamine, is the smallest structural unit of peptidoglycans showing the immunostimulating activity. Muramyl dipeptide analogues without the hydrophilic N-acetylmuramyl moiety are called desmuramyl peptides. Here, we provide review of desmuramyl peptides which were synthesized in order to improve the pharmacological properties of parent muramyl dipeptide, including our results regarding adamantane containing derivatives. Approach for future design of novel immunostimulators based on multiple pathogen recognition receptor activation was also considered.

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

Ključne riječi
adjuvant; desmuramyl peptides; immunostimulation; pathogen recognition receptors

Hrčak ID: 226603

URI
https://hrcak.srce.hr/226603

Posjeta: 475 *