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https://doi.org/10.24099/vet.arhiv.0867

An investigation of thiol/disulfide homeostasis and ischemia-modified albumin levels to assess the oxidative stress in dogs with canine distemper

Şükrü Değirmençay   ORCID icon orcid.org/0000-0002-3920-6343 ; Department of Internal Medicine, Faculty of Veterinary Medicine, Atatürk University, Erzurum, Turkey
Güzin Çamkerten ; Aksaray Technical Sciences Vocational School, Aksaray University, Aksaray, Turkey
İlker Çamkerten ; Department of Internal Medicine, Faculty of Veterinary Medicine, Aksaray University, Aksaray, Turkey
M. Sinan Aktaş ; Department of Internal Medicine, Faculty of Veterinary Medicine, Atatürk University, Erzurum, Turkey

Puni tekst: engleski, pdf (985 KB) str. 39-49 preuzimanja: 0* citiraj
APA 6th Edition
Değirmençay, Ş., Çamkerten, G., Çamkerten, İ. i Aktaş, M.S. (2021). An investigation of thiol/disulfide homeostasis and ischemia-modified albumin levels to assess the oxidative stress in dogs with canine distemper. Veterinarski arhiv, 91 (1), 39-49. https://doi.org/10.24099/vet.arhiv.0867
MLA 8th Edition
Değirmençay, Şükrü, et al. "An investigation of thiol/disulfide homeostasis and ischemia-modified albumin levels to assess the oxidative stress in dogs with canine distemper." Veterinarski arhiv, vol. 91, br. 1, 2021, str. 39-49. https://doi.org/10.24099/vet.arhiv.0867. Citirano 11.04.2021.
Chicago 17th Edition
Değirmençay, Şükrü, Güzin Çamkerten, İlker Çamkerten i M. Sinan Aktaş. "An investigation of thiol/disulfide homeostasis and ischemia-modified albumin levels to assess the oxidative stress in dogs with canine distemper." Veterinarski arhiv 91, br. 1 (2021): 39-49. https://doi.org/10.24099/vet.arhiv.0867
Harvard
Değirmençay, Ş., et al. (2021). 'An investigation of thiol/disulfide homeostasis and ischemia-modified albumin levels to assess the oxidative stress in dogs with canine distemper', Veterinarski arhiv, 91(1), str. 39-49. https://doi.org/10.24099/vet.arhiv.0867
Vancouver
Değirmençay Ş, Çamkerten G, Çamkerten İ, Aktaş MS. An investigation of thiol/disulfide homeostasis and ischemia-modified albumin levels to assess the oxidative stress in dogs with canine distemper. Veterinarski arhiv [Internet]. 2021 [pristupljeno 11.04.2021.];91(1):39-49. https://doi.org/10.24099/vet.arhiv.0867
IEEE
Ş. Değirmençay, G. Çamkerten, İ. Çamkerten i M.S. Aktaş, "An investigation of thiol/disulfide homeostasis and ischemia-modified albumin levels to assess the oxidative stress in dogs with canine distemper", Veterinarski arhiv, vol.91, br. 1, str. 39-49, 2021. [Online]. https://doi.org/10.24099/vet.arhiv.0867

Sažetak
This study aimed to investigate the diagnostic value of thiol/disulfide homeostasis (TDH) and ischemia-modified albumin (IMA) levels in evaluating oxidative stress in dogs with canine distemper. The study materials consisted of 24 cross-breed dogs: 18 dogs with canine distemper (CD group) and 6 healthy dogs as the control. Blood samples for analysis of antioxidant-oxidant parameters were taken from both groups. In addition to TDH parameters (native thiol [NT], total thiol [TT], and disulfide [Ds] levels and Ds/NT, Ds/TT, and NT/TT ratios), IMA and albumin (ALB) levels were also determined in the blood serum of the groups. The IMA levels of the CD group were significantly higher than the control group (P<0.05). Antioxidant parameters (NT, TT) and oxidant parameters (Ds, Ds/NT, and Ds/TT) both exhibited a significant positive correlation among themselves (P<0.01). The areas under the ROC curve of IMA, Ds/ NT, and Ds/TT were 0.78, 0.62, and 0.62 respectively. The high levels of IMA, Ds, Ds/NT, and Ds/TT and low levels of NT, TT, NT/TT and ALB in dogs with canine distemper can be used to assess the oxidative stress caused by the disease. Overall, the diagnostic performances of IMA, Ds/NT, and Ds/TT for detection of increased oxidative stress were similar, but IMA was superior.

Ključne riječi
canine distemper; oxidative stress; thiol/disulfide homeostasis; ischemia-modified albumin

Hrčak ID: 255222

URI
https://hrcak.srce.hr/255222

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