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Epilepsy Due to Malformations of Cortical Development – Correlation of Clinical, MRI and Tc-99mECD SPECT Findings

Davor Sporiš
Sanja Hajnšek
Marina Boban
Silvio Bašić
Ratimir Petrović
Marko Radoš
Tomislav Babić

Puni tekst: engleski, pdf (158 KB) str. 345-350 preuzimanja: 455* citiraj
APA 6th Edition
Sporiš, D., Hajnšek, S., Boban, M., Bašić, S., Petrović, R., Radoš, M. i Babić, T. (2008). Epilepsy Due to Malformations of Cortical Development – Correlation of Clinical, MRI and Tc-99mECD SPECT Findings. Collegium antropologicum, 32 (2), 345-350. Preuzeto s https://hrcak.srce.hr/27216
MLA 8th Edition
Sporiš, Davor, et al. "Epilepsy Due to Malformations of Cortical Development – Correlation of Clinical, MRI and Tc-99mECD SPECT Findings." Collegium antropologicum, vol. 32, br. 2, 2008, str. 345-350. https://hrcak.srce.hr/27216. Citirano 19.11.2019.
Chicago 17th Edition
Sporiš, Davor, Sanja Hajnšek, Marina Boban, Silvio Bašić, Ratimir Petrović, Marko Radoš i Tomislav Babić. "Epilepsy Due to Malformations of Cortical Development – Correlation of Clinical, MRI and Tc-99mECD SPECT Findings." Collegium antropologicum 32, br. 2 (2008): 345-350. https://hrcak.srce.hr/27216
Harvard
Sporiš, D., et al. (2008). 'Epilepsy Due to Malformations of Cortical Development – Correlation of Clinical, MRI and Tc-99mECD SPECT Findings', Collegium antropologicum, 32(2), str. 345-350. Preuzeto s: https://hrcak.srce.hr/27216 (Datum pristupa: 19.11.2019.)
Vancouver
Sporiš D, Hajnšek S, Boban M, Bašić S, Petrović R, Radoš M i sur. Epilepsy Due to Malformations of Cortical Development – Correlation of Clinical, MRI and Tc-99mECD SPECT Findings. Collegium antropologicum [Internet]. 2008 [pristupljeno 19.11.2019.];32(2):345-350. Dostupno na: https://hrcak.srce.hr/27216
IEEE
D. Sporiš, et al., "Epilepsy Due to Malformations of Cortical Development – Correlation of Clinical, MRI and Tc-99mECD SPECT Findings", Collegium antropologicum, vol.32, br. 2, str. 345-350, 2008. [Online]. Dostupno na: https://hrcak.srce.hr/27216. [Citirano: 19.11.2019.]

Sažetak
Malformations of cortical development (MCD) have been increasingly recognized as an important cause of intractable
epilepsy. The aim of our study was to define epileptogenicity of MCDs by correlating MRI, EEG and semiology of epileptic
attacks, and to determine the effect of MCD on drug resistant epilepsy. We also intended to reveal the utility of interictal
single photo emission computed tomography (SPECT) in verification of MCD lesions and relative prevalence of
different MCDs. Based on interictal EEG finding, semiology of the epileptic attacks and brain magnetic resonance imaging
(MRI) »electroclinical epileptogenicity« of MCD was defined. Brain MRI revealed cortical dysplasia (CD) in nine patients,
polymicrogyria in four patients, lissencephaly and schizencephaly in one patient each. Three patients had a combination
of malformations. The localization of SPECT hypoperfusion corresponded to MCD lesion in ten (66.67%)
patients. Electroclinically confirmed epileptogenicity of MCD overlapped with MR and interictal SPECT findings in
fourteen (93.3%) and nine (60.0%) patients, respectively. Our study results demonstrated the MCD lesions to be highly
epileptogenic and a frequent cause of intractability.

Ključne riječi
cortical malformations; intractable epilepsy; epileptogenicity; EEG; MRI; SPECT

Hrčak ID: 27216

URI
https://hrcak.srce.hr/27216

Posjeta: 650 *