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Photodynamic Therapy Combined with Intravitreal Bevacizumab (Avastin) in Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration

Ratimir Lazić
Nikica Gabrić
Iva Dekaris
Morena Gavrić
Damir Bosnar

Puni tekst: engleski, pdf (410 KB) str. 71-75 preuzimanja: 288* citiraj
APA 6th Edition
Lazić, R., Gabrić, N., Dekaris, I., Gavrić, M. i Bosnar, D. (2007). Photodynamic Therapy Combined with Intravitreal Bevacizumab (Avastin) in Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration. Collegium antropologicum, 31 - Supplement 1 (1), 71-75. Preuzeto s https://hrcak.srce.hr/27428
MLA 8th Edition
Lazić, Ratimir, et al. "Photodynamic Therapy Combined with Intravitreal Bevacizumab (Avastin) in Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration." Collegium antropologicum, vol. 31 - Supplement 1, br. 1, 2007, str. 71-75. https://hrcak.srce.hr/27428. Citirano 20.10.2019.
Chicago 17th Edition
Lazić, Ratimir, Nikica Gabrić, Iva Dekaris, Morena Gavrić i Damir Bosnar. "Photodynamic Therapy Combined with Intravitreal Bevacizumab (Avastin) in Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration." Collegium antropologicum 31 - Supplement 1, br. 1 (2007): 71-75. https://hrcak.srce.hr/27428
Harvard
Lazić, R., et al. (2007). 'Photodynamic Therapy Combined with Intravitreal Bevacizumab (Avastin) in Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration', Collegium antropologicum, 31 - Supplement 1(1), str. 71-75. Preuzeto s: https://hrcak.srce.hr/27428 (Datum pristupa: 20.10.2019.)
Vancouver
Lazić R, Gabrić N, Dekaris I, Gavrić M, Bosnar D. Photodynamic Therapy Combined with Intravitreal Bevacizumab (Avastin) in Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration. Collegium antropologicum [Internet]. 2007 [pristupljeno 20.10.2019.];31 - Supplement 1(1):71-75. Dostupno na: https://hrcak.srce.hr/27428
IEEE
R. Lazić, N. Gabrić, I. Dekaris, M. Gavrić i D. Bosnar, "Photodynamic Therapy Combined with Intravitreal Bevacizumab (Avastin) in Treatment of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration", Collegium antropologicum, vol.31 - Supplement 1, br. 1, str. 71-75, 2007. [Online]. Dostupno na: https://hrcak.srce.hr/27428. [Citirano: 20.10.2019.]

Sažetak
To evaluate photodynamic therapy with verteporfin combined with intravitreal bevacizumab in minimally classic
and occult choroidal neovascularization secondary to age-related macular degeneration. 46 eyes of 46 patients (mean age
74.5) included in this prospective, noncomparative, interventional case series. Median follow-up was 24 weeks (12–36).
Verteporfin photodynamic therapy (PDT) was followed by 0.05 mL (1.25 mg) of bevacizumab injected intravitreally
within 24 hours and again after 6 weeks. Whole procedure was repeated in 3-month intervals in case of leakage. Visual
acuity (VA) improved in majority of patients (baseline VA 1.041 log MAR) by mean increase of 1.45 lines (last follow-up)
(p=0.001). Central foveal thickness (CFT) and total macular volume (TMV) decreased by 53 μm (p=0.03) and 1.04 mm3
(p<0.001) respectively. No serious complications were observed.Combined treatment may improve outcome of monotherapy.
Significant improvement in VA, CFT and TMA was noted in majority of patients and maintained during follow-
up.

Ključne riječi
bevacizumab; photodynamic therapy; choroidal neovascularization

Hrčak ID: 27428

URI
https://hrcak.srce.hr/27428

Posjeta: 417 *