Stručni rad

Clinical and Epidemiological Characteristics of Brucellosis in Hospitalised Patients

Sead Ahmetagić ; Javna zdravstvena ustanova Univerzitetsko klinički centar Tuzla, Klinika za infektivne bolesti, Tuzla
Dilista Piljić ; Javna zdravstvena ustanova Univerzitetsko klinički centar Tuzla, Klinika za infektivne bolesti, Tuzla
Arnela Smirko-Nuhanović ; Javna zdravstvena ustanova Univerzitetsko klinički centar Tuzla, Klinika za infektivne bolesti, Tuzla
Aldina Ahmetagić ; Javna zdravstvena ustanova Univerzitetsko klinički centar Tuzla, Služba za kliničku farmakologiju, Tuzla
Blaško Topalović ; Javna zdravstvena ustanova Univerzitetsko klinički centar Tuzla, Zavod za javno zdravstvo Tuzlanskog kantona, Tuzla

Sažetak

The clinical and epidemiological characteristics of brucellosis were retrospectively analysed in 91 patients hospitalised in the Clinic for Infectious Diseases at the University Clinical Centre Tuzla from January 1st 2000 to August 1st 2008. The diagnosis of brucellosis was confirmed by positive results of bloodculture and/or by serology testing (ELISA, Rose Bengal plate agglutination). The great majority, 74 (81,3 %), of the patients were from 5 municipalities of Canton Tuzla: Živinice, Tuzla, Lukavac, Kalesija and Srebrenik. The majority of patients (93,0 %) were inhabitants of rural regions. The males were significantly dominant (82,4 %). Most of the patients were in age group 20 – 29 years and 50 – 59 years (25,3 % respectively). The patients were mostly hospitalized during spring season, especially in April (24,1 %) and May (23,0 %). Contact with infected animals was registered in 82,4% of patients. The leading symptoms and signs of the disease were fever, arthralgias, weakness, night sweating, headache, hepatosplenomegaly, and the most important pathological laboratory findings were high erythrocyte sedimentation rate and elevated value of C-reactive protein. The adult patients were treated with a combination of streptomycin or gentamicin with doxycycline, and the children were treated with gentamicin and trimethoprim-sulfamethoxazole during 6 weeks. Complications were documented in 23,0 % of males and 1,1% of females. Orchiepididymitis was found in 6,5 %, pneumonia in 4,3 %, peripheral arthritis 4,3 %, spondylitis 3,2 %, coxitis 2,1 %, epidural abscess in 2,1 %, and spondylodiscitis in 1% of patients. Relapse of the disease was registered in 13,1 % of patients. All patients were cured. Brucellosis is a growing public health problem in Canton Tuzla and in Bosnia and Herzegovina.

Ključne riječi

brucellosis; clinical characteristics; epidemiology; Canton Tuzla

Hrčak ID:

30515

URI

https://hrcak.srce.hr/30515

Datum izdavanja:

3.9.2008.

Podaci na drugim jezicima: hrvatski

Posjeta: 4.310 *