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Arhiv za higijenu rada i toksikologiju, Vol. 49 No. 2, 1998.
Izvorni znanstveni članak
Effects of Gamma-Radiation on Ovarian Follicles
Young-Keun Lee
Hwa-Hyoung Chang
Won-Rok Kim
Jin Kyu Kim
Yong-Dal Yoon
| Puni tekst: engleski, pdf (319 KB) | str. 147-153 | citiraj | |
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APA 6th Edition Lee, Y., Chang, H., Kim, W., Kyu Kim, J. i Yoon, Y. (1998). Effects of Gamma-Radiation on Ovarian Follicles. Arhiv za higijenu rada i toksikologiju, 49 (2), 147-153. Preuzeto s https://hrcak.srce.hr/3310 MLA 8th Edition Lee, Young-Keun, et al. "Effects of Gamma-Radiation on Ovarian Follicles." Arhiv za higijenu rada i toksikologiju, vol. 49, br. 2, 1998, str. 147-153. https://hrcak.srce.hr/3310. Citirano 20.02.2019. Chicago 17th Edition Lee, Young-Keun, Hwa-Hyoung Chang, Won-Rok Kim, Jin Kyu Kim i Yong-Dal Yoon. "Effects of Gamma-Radiation on Ovarian Follicles." Arhiv za higijenu rada i toksikologiju 49, br. 2 (1998): 147-153. https://hrcak.srce.hr/3310 Harvard Lee, Y., et al. (1998). 'Effects of Gamma-Radiation on Ovarian Follicles', Arhiv za higijenu rada i toksikologiju, 49(2), str. 147-153. Preuzeto s: https://hrcak.srce.hr/3310 (Datum pristupa: 20.02.2019.) Vancouver Lee Y, Chang H, Kim W, Kyu Kim J, Yoon Y. Effects of Gamma-Radiation on Ovarian Follicles. Arh Hig Rada Toksikol. [Internet]. 1998 [pristupljeno 20.02.2019.];49(2):147-153. Dostupno na: https://hrcak.srce.hr/3310 IEEE Y. Lee, H. Chang, W. Kim, J. Kyu Kim i Y. Yoon, "Effects of Gamma-Radiation on Ovarian Follicles", Arhiv za higijenu rada i toksikologiju, vol.49, br. 2, str. 147-153, 1998. [Online]. Dostupno na: https://hrcak.srce.hr/3310. [Citirano: 20.02.2019.] |
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Sažetak
In order to observe the morphological and endocrinological changes of the rat and mouse ovarian follicles by gamma-radiation, rats were whole-body irradiated with doses of 3.2 Gy and 8.0 Gy and mice with 2.9 Gy and 7.2 Gy. Sections of ovaria were examined by light microscopy. Concentrations of progesterone, testosterone, and estradiol in ovarian homogenate were determined by radioimmunoassay techniques. Gamma-radiation resulted in the increased percentage of atretic follicles in the groups killed on day 0, day 4, and day 8 after irradiation. The decrease in granulosa cell viability was found in animals killed on day 4 after irradiation. The finding of the high ratio of testosterone to estradiol compared to that of progesterone to testosterone suggests that aromatase activity — steroid biosynthesis from testosterone to estradiol — in granulosa cell could be affected by gamma-radiation.
Ključne riječi
estradiol; gamma-radiation; mice; ovarian follicles; ovarian histology; progesterone; rats; testosterone
Hrčak ID: 3310
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