Sažetak sa skupa
Salivary Peroxidase Levels in Patients With Oral Lichen Planus
Vanja Vučičević-Boras
R. Zadro
Ana Cekić-Arambašin
T. Devčić
Katarina Zjača
Sažetak
Oral lichen planus (OLP) is a chronic inflammatory disease whose etiology has not yet been identified. It is characterizied by immunoreactivity directed against basal keratinocytes and mediated by T-lymphocytes. In health, salivary peroxidase together with other salivary antimicrobial enzymes maintains the ecological balance in the
oral cavity.
The aim of this study was to evaluate salivary peroxidase levels in patients with OLP. In 30 patients with OLP, salivary peroxidase levels in whole unstimulated saliva were determined and compared to 28 healthy controls. Each participant collected saliva using the simple method of spitting while sitting unstimulated whole saliva into
calibrated tubes during five minutes between 8-11 A.M. Salivary samples were then centrifuged on 800 turns during ten minutes and supernatans were frozen at -70°C until analysis. Salivary peroxidase levels were determined according to Putter and Becker. Statistical analysis was performed using Student t-tes and p-values below 0.05
were considered statistically significant. No significant differnces between patients with OLP and controls in salivary flow rate, as well as in salivary peroxidase levels were found. We can conclude that salivary peroxidase levels in patients with OLP did not have an impact on changes seen in the oral cavity of these patients.
Ključne riječi
Hrčak ID:
3577
URI
Datum izdavanja:
15.9.2003.
Posjeta: 1.421 *