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Efficacy and Safety of Budesonide/Formeterol Combination Therapy in Asthma Patients

Marko Jakopović ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Fadila Pavičić ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Gzim Redžepi ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Sanja Pleština ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Mateja Janković ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Zrinka Franić ; School of Medicine, Zagreb, Croatia
Mirko Šamija ; University Hospital for Tumors, Zagreb, Croatia
Miroslav Samaržija ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia

Puni tekst: engleski, pdf (71 KB) str. 587-591 preuzimanja: 309* citiraj
APA 6th Edition
Jakopović, M., Pavičić, F., Redžepi, G., Pleština, S., Janković, M., Franić, Z., ... Samaržija, M. (2009). Efficacy and Safety of Budesonide/Formeterol Combination Therapy in Asthma Patients. Collegium antropologicum, 33 (2), 587-591. Preuzeto s https://hrcak.srce.hr/40561
MLA 8th Edition
Jakopović, Marko, et al. "Efficacy and Safety of Budesonide/Formeterol Combination Therapy in Asthma Patients." Collegium antropologicum, vol. 33, br. 2, 2009, str. 587-591. https://hrcak.srce.hr/40561. Citirano 29.03.2020.
Chicago 17th Edition
Jakopović, Marko, Fadila Pavičić, Gzim Redžepi, Sanja Pleština, Mateja Janković, Zrinka Franić, Mirko Šamija i Miroslav Samaržija. "Efficacy and Safety of Budesonide/Formeterol Combination Therapy in Asthma Patients." Collegium antropologicum 33, br. 2 (2009): 587-591. https://hrcak.srce.hr/40561
Harvard
Jakopović, M., et al. (2009). 'Efficacy and Safety of Budesonide/Formeterol Combination Therapy in Asthma Patients', Collegium antropologicum, 33(2), str. 587-591. Preuzeto s: https://hrcak.srce.hr/40561 (Datum pristupa: 29.03.2020.)
Vancouver
Jakopović M, Pavičić F, Redžepi G, Pleština S, Janković M, Franić Z i sur. Efficacy and Safety of Budesonide/Formeterol Combination Therapy in Asthma Patients. Collegium antropologicum [Internet]. 2009 [pristupljeno 29.03.2020.];33(2):587-591. Dostupno na: https://hrcak.srce.hr/40561
IEEE
M. Jakopović, et al., "Efficacy and Safety of Budesonide/Formeterol Combination Therapy in Asthma Patients", Collegium antropologicum, vol.33, br. 2, str. 587-591, 2009. [Online]. Dostupno na: https://hrcak.srce.hr/40561. [Citirano: 29.03.2020.]

Sažetak
Budesonide/formoterol as single inhaler was developed for treating asthma patients who are not adequately controlled on glucocorticoides alone. The aim of this study was to evaluate efficacy, safety and patient/physician satisfaction of budesonide/formoterol therapy.Total of 268 asthma patients (120 men, mean age 38,8 ± 37,2 years, and 148 women, mean age 42,2 ± 32 years) were included in the study. All patients received budesonide/formoterol bid (640 mcg of budesonide and 18 mcg of formoterol daily) during run-in period for three weeks. Patients were followed during 14 weeks at 5 visits.At each visit lung function (FEV1 and PEF) was measured,presence of side affects was recorded and questionnaire was given to patients and physicians to estimate the level of satisfaction with budesonide/formoterol therapy (1 very unsatisfied to 5 very satisfied). Significant improvement was noticed in FEV1, from 76,25% of predicted value to 86,94% (p<0,01); and in PEF from 380,84 L/min to 442,29 L/min (p<0,01) in all patients. At the end of the study patients’ satisfaction with budesonide/formeterol therapy was significantly improved comparing with satisfaction with previously taken therapy,in average grade, from 2,94 to 4,56 (p<0,01),and similar results were noticed with physicians’ satisfaction, from 2,60 to 4,41 (p<0,01). Budesonide/formoterol in single inhaler, significantly improved lung function in patients with asthma.

Ključne riječi
asthma; asthma control; budesonide/formoterol

Hrčak ID: 40561

URI
https://hrcak.srce.hr/40561

Posjeta: 614 *