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Apolipoprotein E Polymorphism in Relation to Plasma Lipid Levels and Other Risk Factors of Atherosclerosis in Two Ethnic Groups from Slovakia

Daniela Siváková
Mária Zacharová
Juraj Gašparovič
Katarína Rašlová
Ladislava Wsólová
Zuzana Bašistová
Pavel Blažíček

Puni tekst: engleski, pdf (106 KB) str. 387-394 preuzimanja: 424* citiraj
APA 6th Edition
Siváková, D., Zacharová, M., Gašparovič, J., Rašlová, K., Wsólová, L., Bašistová, Z. i Blažíček, P. (2006). Apolipoprotein E Polymorphism in Relation to Plasma Lipid Levels and Other Risk Factors of Atherosclerosis in Two Ethnic Groups from Slovakia. Collegium antropologicum, 30 (2), 387-394. Preuzeto s https://hrcak.srce.hr/4254
MLA 8th Edition
Siváková, Daniela, et al. "Apolipoprotein E Polymorphism in Relation to Plasma Lipid Levels and Other Risk Factors of Atherosclerosis in Two Ethnic Groups from Slovakia." Collegium antropologicum, vol. 30, br. 2, 2006, str. 387-394. https://hrcak.srce.hr/4254. Citirano 21.06.2021.
Chicago 17th Edition
Siváková, Daniela, Mária Zacharová, Juraj Gašparovič, Katarína Rašlová, Ladislava Wsólová, Zuzana Bašistová i Pavel Blažíček. "Apolipoprotein E Polymorphism in Relation to Plasma Lipid Levels and Other Risk Factors of Atherosclerosis in Two Ethnic Groups from Slovakia." Collegium antropologicum 30, br. 2 (2006): 387-394. https://hrcak.srce.hr/4254
Harvard
Siváková, D., et al. (2006). 'Apolipoprotein E Polymorphism in Relation to Plasma Lipid Levels and Other Risk Factors of Atherosclerosis in Two Ethnic Groups from Slovakia', Collegium antropologicum, 30(2), str. 387-394. Preuzeto s: https://hrcak.srce.hr/4254 (Datum pristupa: 21.06.2021.)
Vancouver
Siváková D, Zacharová M, Gašparovič J, Rašlová K, Wsólová L, Bašistová Z i sur. Apolipoprotein E Polymorphism in Relation to Plasma Lipid Levels and Other Risk Factors of Atherosclerosis in Two Ethnic Groups from Slovakia. Collegium antropologicum [Internet]. 2006 [pristupljeno 21.06.2021.];30(2):387-394. Dostupno na: https://hrcak.srce.hr/4254
IEEE
D. Siváková, et al., "Apolipoprotein E Polymorphism in Relation to Plasma Lipid Levels and Other Risk Factors of Atherosclerosis in Two Ethnic Groups from Slovakia", Collegium antropologicum, vol.30, br. 2, str. 387-394, 2006. [Online]. Dostupno na: https://hrcak.srce.hr/4254. [Citirano: 21.06.2021.]

Sažetak
The influence of apolipoprotein E (ApoE) genotypes on plasma lipid levels and interaction with other environmental factors was determined in two Slovakian population samples; 146 Romany and 351 Slovak individuals. The two samples differ significantly in the distribution of E3/3 genotypes (p_0.014) and E3/2 (p_0.035). Analysis of variance did not reveal any significant effect of the ApoE genotypes on any of the plasma lipid levels in the Romany individuals. In the Slovak sample the variation in plasma low-density lipoprotein cholesterol (LDL-C) levels was significantly associated with the ApoE genotypes (p=0.012). We detected decreased LDL-C concentrations in males with E2 genotype when compared with E3 and E4 carriers (p=0.008). Further, the E2 genotype was found to be associated with high triglycerides levels (p=0.009). The ethnic samples differ significantly in the prevalence of metabolic syndrome and in the case of males of diabetes. Both the Romany and the Slovak males can be considered as having a more atherogenic profile compared with the females

Ključne riječi
ApoE; lipids; risk factors; atherosclerosis; Slovakia

Hrčak ID: 4254

URI
https://hrcak.srce.hr/4254

Posjeta: 706 *