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Intraoperative Imprint Cytological Assessment of the Subareolar Tissue of the Nipple Areola Complex (NAC)

Čedna Tomasović-Lončarić
Rudolf Milanović
Smiljka Lambaša
Šimun Križanac
Tajana Štoos-Veić
Gordana Kaić
Karmen Trutin Ostović

Puni tekst: engleski, pdf (64 KB) str. 431-435 preuzimanja: 178* citiraj
APA 6th Edition
Tomasović-Lončarić, Č., Milanović, R., Lambaša, S., Križanac, Š., Štoos-Veić, T., Kaić, G. i Trutin Ostović, K. (2010). Intraoperative Imprint Cytological Assessment of the Subareolar Tissue of the Nipple Areola Complex (NAC). Collegium antropologicum, 34 (2), 431-435. Preuzeto s https://hrcak.srce.hr/56458
MLA 8th Edition
Tomasović-Lončarić, Čedna, et al. "Intraoperative Imprint Cytological Assessment of the Subareolar Tissue of the Nipple Areola Complex (NAC)." Collegium antropologicum, vol. 34, br. 2, 2010, str. 431-435. https://hrcak.srce.hr/56458. Citirano 20.11.2019.
Chicago 17th Edition
Tomasović-Lončarić, Čedna, Rudolf Milanović, Smiljka Lambaša, Šimun Križanac, Tajana Štoos-Veić, Gordana Kaić i Karmen Trutin Ostović. "Intraoperative Imprint Cytological Assessment of the Subareolar Tissue of the Nipple Areola Complex (NAC)." Collegium antropologicum 34, br. 2 (2010): 431-435. https://hrcak.srce.hr/56458
Harvard
Tomasović-Lončarić, Č., et al. (2010). 'Intraoperative Imprint Cytological Assessment of the Subareolar Tissue of the Nipple Areola Complex (NAC)', Collegium antropologicum, 34(2), str. 431-435. Preuzeto s: https://hrcak.srce.hr/56458 (Datum pristupa: 20.11.2019.)
Vancouver
Tomasović-Lončarić Č, Milanović R, Lambaša S, Križanac Š, Štoos-Veić T, Kaić G i sur. Intraoperative Imprint Cytological Assessment of the Subareolar Tissue of the Nipple Areola Complex (NAC). Collegium antropologicum [Internet]. 2010 [pristupljeno 20.11.2019.];34(2):431-435. Dostupno na: https://hrcak.srce.hr/56458
IEEE
Č. Tomasović-Lončarić, et al., "Intraoperative Imprint Cytological Assessment of the Subareolar Tissue of the Nipple Areola Complex (NAC)", Collegium antropologicum, vol.34, br. 2, str. 431-435, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/56458. [Citirano: 20.11.2019.]

Sažetak
One of the criteria of selection for skin sparing mastectomy (SSM) with nipple areola complex (NAC) preservation is to exclude the neoplastic involvement of subareolar tissue (NAC base) in order to minimize the possibility of local recurrence. The most common way to assess the possible neoplastic involvement is intraoperative frozen section of the NAC base tissue. Because of its limitations, particularly the false negative results due to unsampling, we tried to use intraoperative imprint cytology for more thorough intraoperative assessment. The aim was to compare intraoperative imprint findings with the definitive histology of the NAC base, to evaluate diagnostic accuracy of this method and possibility to substitute frozen section for intraoperative assessment of NAC base. A prospective clinical study was conducted of 208 consecutive female patients who underwent open biopsy because of carcinoma. Intraoperative imprints were taken from the excised subareolar tissue which was then routinely processed for definitive histology. Imprint findings designated positive, negative, suspicious or atypia, were compared with definitive histological findings. Our results with 7.5% false negative rate, 9.8% false positive rate, sensitivity of 50% and specificity of 87.58% argue that imprint cytology might not be sufficient as an exclusive method for the intraoperative assessment of the NAC base though it should be used routinely in conjunction with frozen section examination.

Ključne riječi
intraoperative imprint cytology; NAC base; nipple areola complex preservation

Hrčak ID: 56458

URI
https://hrcak.srce.hr/56458

Posjeta: 313 *