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QSAR Modeling of Antifungal Activity of Some Heterocyclic Compounds

Oleg Ursu
Adina Costescu
Mircea V. Diudea
Bazil Parv

Puni tekst: engleski, pdf (173 KB) str. 483-466 preuzimanja: 1.711* citiraj
APA 6th Edition
Ursu, O., Costescu, A., Diudea, M.V. i Parv, B. (2006). QSAR Modeling of Antifungal Activity of Some Heterocyclic Compounds. Croatica Chemica Acta, 79 (3), 483-466. Preuzeto s https://hrcak.srce.hr/5659
MLA 8th Edition
Ursu, Oleg, et al. "QSAR Modeling of Antifungal Activity of Some Heterocyclic Compounds." Croatica Chemica Acta, vol. 79, br. 3, 2006, str. 483-466. https://hrcak.srce.hr/5659. Citirano 07.03.2021.
Chicago 17th Edition
Ursu, Oleg, Adina Costescu, Mircea V. Diudea i Bazil Parv. "QSAR Modeling of Antifungal Activity of Some Heterocyclic Compounds." Croatica Chemica Acta 79, br. 3 (2006): 483-466. https://hrcak.srce.hr/5659
Harvard
Ursu, O., et al. (2006). 'QSAR Modeling of Antifungal Activity of Some Heterocyclic Compounds', Croatica Chemica Acta, 79(3), str. 483-466. Preuzeto s: https://hrcak.srce.hr/5659 (Datum pristupa: 07.03.2021.)
Vancouver
Ursu O, Costescu A, Diudea MV, Parv B. QSAR Modeling of Antifungal Activity of Some Heterocyclic Compounds. Croatica Chemica Acta [Internet]. 2006 [pristupljeno 07.03.2021.];79(3):483-466. Dostupno na: https://hrcak.srce.hr/5659
IEEE
O. Ursu, A. Costescu, M.V. Diudea i B. Parv, "QSAR Modeling of Antifungal Activity of Some Heterocyclic Compounds", Croatica Chemica Acta, vol.79, br. 3, str. 483-466, 2006. [Online]. Dostupno na: https://hrcak.srce.hr/5659. [Citirano: 07.03.2021.]

Sažetak
QSAR analysis of a set of benzoxazoles, benzimidazoles, oxazolo[4,5-b]pyridines and benzothiazoles, showing growth inhibitory activity against Candida albicans, was performed using a multiple regression procedure. Topological indices (TIs) and principal component analysis (PCA) on TIs were used in modeling antifungal activity. Selection of TIs relevant to developing QSAR models was made using the largest PC factor loading scores. Correlation coefficient 0.97 obtained in the validation procedure indicated the excellent quality of the derived QSAR models.

Ključne riječi
antifungal activity; QSAR/QSPR; PCA

Hrčak ID: 5659

URI
https://hrcak.srce.hr/5659

Posjeta: 2.052 *