Izvorni znanstveni članak
HARMFUL HABITS IN PREGNANCY
Marcel Leppée
; Zavod za javno zdravstvo grada Zagreba
Mirela Erić
; Zavod za anatomiju Medicinskog fakulteta Univerziteta u Novom Sadu
Josip Ćulig
; Zavod za farmakologiju Medicinskog fakulteta Sveučilišta »Josip Juraj Strossmayer« u Osijeku
Sažetak
Objective. The aim of the study was to assess the prevalence of alcohol, nicotine and opioid substance use in pregnancy, and the rate of congenital malformations in children at in utero exposure to these xenobiotics. Methods. One part of the study (one year study) was performed at University Department of Gynecology and Obstetrics, Genetic Counseling Unit, and Department of Pathology and Histology in Novi Sad, Serbia. The other part of the study (one month study) was performed at four maternity hospitals in Zagreb, Croatia. Only pregnant women using alcohol, nicotine and opioid substances during pregnancy were included in the study. Final analysis included data on 855 (707+148) pregnant women. Following delivery or abortion, the newborns and fetuses were thoroughly examined and followed-up for the occurrence of minor or major malformations. Pregnant women were studied by questionnaire at the moment of birth. Questionnaire was consisted by two types of data: interview of parturient woman and hospital records. Results. Data ¬analysis showed the use of studied xenobiotics during pregnancy in 855 (12,2%) of 6992 (6099+893) women: alcohol in 21 (0,3%), cigarette smoking in 829 (11,9%) and opioid substances in 5 (0,1%) women. Malformations were found in 105 (12,3%) fetuses and newborns. The rate of congenital malformations exceeded their prevalence in the general population. Conclusion. Based on these results, the true cause of these malformations could not be definitely identified; however, the use of alcohol, nicotine and opioid substances during pregnancy should be avoided.
Ključne riječi
pregnancy; harmful behaviour; congenital malformations
Hrčak ID:
62190
URI
Datum izdavanja:
1.9.2008.
Posjeta: 2.996 *