Stručni rad
The Role of Optical Coherence Tomography (OCT) in Optic Neuritis (ON)
Branimir Cerovski
; University of Zagreb, Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Marija Barišić Kutija
; University of Zagreb, Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Tomislav Vidović
; University of Zagreb, Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Smiljka Popović-Suić
; University of Zagreb, Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Sonja Jandroković
; University of Zagreb, Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Rajko Kordić
; University of Zagreb, Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Sania Vidas
; University of Zagreb, Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
Sažetak
Axonal and neuronal degeneration are important features of multiple sclerosis (MS) and other neurologic disorders that affect the anterior visual pathway. Optical coherence tomography (OCT) is a non-invasive technique that allows imaging of the retinal layers. Our aim was to examine retinal nerve fiber layer (RNFL) thickness and macular volume (MV), measred by OCT, in patients with history of optic neuritis (ON). Patients with chronic ON had significantly decreased mean RNFL thickness and total MV when compared to acute ON eyes, controls and unaffected fellow eyes. There was also statistically significant difference between two chronic groups, with lower values in group with history of acute ON. OCT provides us unique insight in structural changes in the anterior visual pathway, therefore it may complement our existing diagnostic tests and, as a potential outcome measure, help develop more effective therapeutic strategies for ON and MS patients.
Ključne riječi
Optical coherence tomography; Optic neuritis; RNFL; macular volume; axonal loss
Hrčak ID:
102857
URI
Datum izdavanja:
22.4.2013.
Posjeta: 2.046 *