Veterinarski arhiv, Vol. 83 No. 4, 2013.
Izvorni znanstveni članak
Comparable efficacy of topical eprinomectin and permethrin for treatment of sarcoptic mange in dogs.
Tahsin B. Deger
; Department of Internal Medicine, Veterinary Faculty, Adnan Menderes University, Isikli, Aydin-Turkey
Kerem Ural
; Department of Internal Medicine, Veterinary Faculty, Adnan Menderes University, Isikli, Aydin-Turkey
Sažetak
The present study was conducted to evaluate the comparative efficacy of topically applied eprinomectin and permethrin for treatment of naturally occuring sarcoptic mange in dogs. A total of 24 dogs of various breeds, age and of both sexes were enrolled. Diagnosis of naturally occuring sarcoptic mange in dogs was made by identifying skin scrapings. All cases were subjected to scoring of the relevant significant clinical signs of scabies such as erythema, pruritis, alopecia, hyperpigmentation and crusting for the whole duration of the study. Dogs in group I (n = 9) received 0.5 mg/kg eprinomectin (5 mg/mL) topically once a week, and group II (n = 8) permethrin at a dosage of 20 mg/kg (100 mg/mL) topicallly once a week, both for a total of 4 weeks. Dogs in group III (n = 7) did not receive any treatment and were left as the control. All the scoring results were statistically evaluated on day 0 and 70, and revealed eprinomectin as the most effective group for evaluating clinical recovery (P<0.05). Evaluation of clinical signs and scoring results suggested complete clinical cure of 100% of dogs in the eprinomectin group, while permetrin was not effective where cure was evident in 2 out of 8 cases. In conclusion, topically applied eprinomectin was highly effective against naturally acquired infestation of S. scabieiby combined assessment of skin scrapings, scoring of skin lesions and clinical signs in comparison to permethrin
Ključne riječi
eprinomectin; permethrin; sarcoptic mange; dogs
Hrčak ID:
105383
URI
Datum izdavanja:
8.7.2013.
Posjeta: 2.410 *