Acta Pharmaceutica, Vol. 65 No. 2, 2015.
Kratko priopćenje
https://doi.org/10.1515/acph-2015-0017
Thermal analysis of N-carbamoyl benzotriazole derivatives
IVAN KOS
; University of Zagreb, Faculty of Pharmacy and Biochemistry, 10000 Zagreb, Croatia
TIN WEITNER
; University of Zagreb, Faculty of Pharmacy and Biochemistry, 10000 Zagreb, Croatia
SANDRA FLINČEC GRGAC
; University of Zagreb, Faculty of Textile Technology, 10000 Zagreb, Croatia
JASNA JABLAN
orcid.org/0000-0003-4741-0819
; University of Zagreb, Faculty of Pharmacy and Biochemistry, 10000 Zagreb, Croatia
Sažetak
Thermal properties of N-carbamoyl benzotriazole derivatives and N,N',N''-tribenzyloxyisocyanuric acid were investigated using thermogravimetric analysis and differential scanning calorimetry. The results revealed a difference between structural analogs of N-carbamoyl benzotriazole derivatives. They seem to be in agreement with the previously proposed formation of N,N',N''-tribenzyloxyisocyanuric acid from 1-(N-benzyloxycarbamoyl) benzotriazole, via an intermediary N-benzyloxyisocyanate acid, during heating. Substantially different thermal properties were observed for structural analogues, 1-(N-methoxycarbamoyl) benzotriazole and 1-(N-ethoxycarbamoyl) benzotriazole. In contrast to N-benzyloxyisocyanate, no corresponding reactions were observed for their decomposition products, i.e., methoxyisocyanate and ethoxyisocyanate.
Ključne riječi
1-(N-benzyloxycarbamoyl) benzotriazole; 1-(N-methoxycarbamoyl) benzotriazole; 1-(N-ethoxycarbamoyl) benzotriazole; N,N',N''-tribenzyloxyisocyanuric acid; thermogravimetric analysis; differential scanning calorimetry; ATR-FTIR
Hrčak ID:
128996
URI
Datum izdavanja:
30.6.2015.
Posjeta: 1.593 *