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https://doi.org/10.1515/acph-2015-0027

Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum

SVJETLANA LUTEROTTI ; University of Zagreb, Faculty of Pharmacy and Biochemistry, HR-10000 Zagreb, Croatia
TONČICA VUKMAN KORDIĆ ; Agency for Medicinal Products and Medical Devices, HR-10000 Zagreb, Croatia
IVKA ZORIČIĆ LETOJA ; Children´s Hospital Srebrnjak, HR-10000 Zagreb, Croatia
SLAVICA DODIG ; Children´s Hospital Srebrnjak, HR-10000 Zagreb, Croatia

Puni tekst: engleski, pdf (267 KB) str. 321-329 preuzimanja: 223* citiraj
APA 6th Edition
LUTEROTTI, S., VUKMAN KORDIĆ, T., ZORIČIĆ LETOJA, I. i DODIG, S. (2015). Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum. Acta Pharmaceutica, 65 (3), 321-329. https://doi.org/10.1515/acph-2015-0027
MLA 8th Edition
LUTEROTTI, SVJETLANA, et al. "Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum." Acta Pharmaceutica, vol. 65, br. 3, 2015, str. 321-329. https://doi.org/10.1515/acph-2015-0027. Citirano 22.09.2019.
Chicago 17th Edition
LUTEROTTI, SVJETLANA, TONČICA VUKMAN KORDIĆ, IVKA ZORIČIĆ LETOJA i SLAVICA DODIG. "Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum." Acta Pharmaceutica 65, br. 3 (2015): 321-329. https://doi.org/10.1515/acph-2015-0027
Harvard
LUTEROTTI, S., et al. (2015). 'Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum', Acta Pharmaceutica, 65(3), str. 321-329. https://doi.org/10.1515/acph-2015-0027
Vancouver
LUTEROTTI S, VUKMAN KORDIĆ T, ZORIČIĆ LETOJA I, DODIG S. Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum. Acta Pharm. [Internet]. 2015 [pristupljeno 22.09.2019.];65(3):321-329. https://doi.org/10.1515/acph-2015-0027
IEEE
S. LUTEROTTI, T. VUKMAN KORDIĆ, I. ZORIČIĆ LETOJA i S. DODIG, "Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum", Acta Pharmaceutica, vol.65, br. 3, str. 321-329, 2015. [Online]. https://doi.org/10.1515/acph-2015-0027

Sažetak
In an attempt to provide a reliable status of metal ions in children, new methods of analysis of children's sera are proposed. New flame atomic-absorption spectrometric (FAAS) methods are simple, cost- and time-effective and, above all, labor-, reagent- and sample-saving. Two methods were selected andvalidated against reference methods: method A for simultaneous determination of Cu and Zn from 5-fold diluted sera, and method B, for assaying zinc alone in 10-fold diluted samples. Both methods are based on a single-step sample pretreatment (deproteinization with 3 mol dm-3 HCl). Method A uses a single-step calibration with a mixed standard. The main advantage of method B is an additional reduction in sample consumption. Both methods were fully validated; accuracy, sensitivity and precision have proven them to becomparable to the reference methods, in terms of analytical performance,and applicable to analyses of children's sera.

Ključne riječi
copper; zinc; Cu/Zn ratio; biochemical parameters; children's serum; lung tuberculosis

Hrčak ID: 134870

URI
https://hrcak.srce.hr/134870

Posjeta: 433 *