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Activities of Serum Esterases in Patients with Hyperlipidaemia

Elsa Reiner ; Institute for Medical Research and Occupational Health, Ksauerska cesta 2, P.O.B. 291, 10001 Zagreb, Croatia
Elizabeta Pavković ; Institute for Medical Research and Occupational Health, Ksauerska cesta 2, P.O.B. 291, 10001 Zagreb, Croatia
Vera Simeon-Rudolf ; Institute for Medical Research and Occupational Health, Ksauerska cesta 2, P.O.B. 291, 10001 Zagreb, Croatia
Mate Sučić ; Vuk Vrhovac Institute, University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Dugi dol 4A, Faculty of Medicine, University of Zagreb, 10000 Zagreb, Croatia
Vaskresenija Lipovac ; Vuk Vrhovac Institute, University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Dugi dol 4A, Faculty of Medicine, University of Zagreb, 10000 Zagreb, Croatia

Sažetak

Esterases were studied in serum samples from 141 patients with hyperlipidaemia and 27 patients with hyperlipidaemia and non-in- sulin-dependent diabetes mellitus. The control group consisted of 322 non-diseased individuals. Paraoxon, beta-naphthylacetate and phenylacetate were used as substrates. Enzyme activities were measured in the absence and presence of EDTA in order to differentiate the EDTA-sensitive (y-sen) from the EDTA-insensitive Ivins) enzymes. Activity ranges for a given enzyme and substrate grossly overlapped between all the studied groups. However, sera from the control group had significantly higher median v-sen and y-ins activities for paraoxon, and higher y-sen and y-ins activities for PA, than the two groups of patients. HDL-cholesterol, total cholesterol, triglycerides and lipidograms were determined in serum samples from the two groups of patients. Serum samples with type V lipidogram had the lowest y-sen and y-ins activities for paraoxon, the lowest HDL-cholesterol and the highest triglyceride concentrations.

Ključne riječi

Hrčak ID:

135963

URI

https://hrcak.srce.hr/135963

Datum izdavanja:

4.3.1996.

Posjeta: 779 *