Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2015.56.181
Postmortem diagnosis of diabetes mellitus and its complications
Cristian Palmiere
orcid.org/0000-0002-5799-9893
; CURML, Centre Universitaire Romand De Medecine LegaleLausanne University HospitalLausanne, Switzerland
Sažetak
Diabetes mellitus has become a major cause of death
worldwide and diabetic ketoacidosis is the most common
cause of death in children and adolescents with type 1 diabetes.
Acute complications of diabetes mellitus as causes
of death may be difficult to diagnose due to missing
characteristic macroscopic and microscopic findings. Biochemical
analyses, including vitreous glucose, blood (or
alternative specimen) beta-hydroxybutyrate, and blood
glycated hemoglobin determination, may complement
postmortem investigations and provide useful information
for determining the cause of death even in corpses
with advanced decompositional changes. In this article,
we performed a review of the literature pertaining to the
diagnostic performance of classical and novel biochemical
parameters that may be used in the forensic casework to
identify disorders in glucose metabolism. We also present
a review focusing on the usefulness of traditional and alternative
specimens that can be sampled and subsequently
analyzed to diagnose acute complications of diabetes mellitus
as causes of death.
Ključne riječi
Hrčak ID:
144064
URI
Datum izdavanja:
15.6.2015.
Posjeta: 1.827 *