Izvorni znanstveni članak

Evaluating the metabolism of high producing Holstein dairy cows following bolus intravenous glucose administration.

Aliasghar Chalmeh ; School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Mehrdad Pourjafar ; School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Saeed Nazifi ; School of Veterinary Medicine, Shiraz University, Shiraz, Iran

Sažetak

Providing energy demands with emphasis on glucose supply can prevent metabolic disorders in high producing dairy cows. Hence, we hypothesized that bolus intravenous glucose administration may change the concentrations of circulating metabolic biomarkers in order to prevent and control metabolic dysfunctions in dairy cows. Twenty-five multiparous, high producing Holstein dairy cows were divided into 5 equal groups containing early, mid and late lactation, and far-off and close-up dry cows. All cows received dextrose 50 % intravenously at 500 mg/kg, 10 mL/kg/hour. Blood samples were collected from all animals prior to and 1, 2, 3 and 4 hours after dextrose 50 % infusion, and sera were separated to determine glucose, insulin, non-esterified fatty acid, β-hydroxybutyric acid, cholesterol, triglyceride, high, low and very low density lipoproteins. Significantly decreasing patterns of non-esterified fatty acid and β-hydroxybutyric acid were seen in early and mid-lactation and close-up dry cows after glucose administration (P<0.05). Rapid and significantly increasing patterns of glucose and insulin concentrations were seen in early and mid-lactation and close up dry cows after glucose administration (P<0.05). In early lactation and close-up dry cows, insulin remained at high concentrations at hour 4. Despite the increased levels of insulin in early and mid-lactation and close-up dry cows, glucose concentrations did not decrease near to base line levels at the 4th hour. There were no significant changes to the patterns of the lipid profile after glucose administration (P>0.05). The results of this study demonstrated that bolus intravenous glucose infusion can influence metabolism in high producing Holstein dairy cows. The changing patterns of circulating metabolic profi le indicated that glucose is an important direct controller of metabolic interactions and responses in dairy cows in various physiological states.

Ključne riječi

glucose; energy demands; metabolism promotion; Holstein dairy cows

Hrčak ID:

149855

URI

https://hrcak.srce.hr/149855

Datum izdavanja:

9.12.2015.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.501 *