Izvorni znanstveni članak
Reproductive toxicological effects in rats after oral exposure to effluents from a coal gasification plant
M. Blanuša
; Institute for Medical Research and Occupational Health, University of Zagreb, Zagreb, Croatia
T. Maljković
; Institute for Medical Research and Occupational Health, Zagreb, Croatia
K. Kostial
; Institute for Medical Research and Occupational Health, Zagreb, Croatia
Sažetak
Health effects of three liquid wastes from a Lurgi coal gasification plant were studied in rats. Fleissner condensate (F), Generator section waste water (G) and Phenosolvan section waste water (P) were given to rats as drinking water through three generations to determine some reproduction parameters (fertility index, number of pups per litter and body weight). Other health effect parameters (body weight, food and fluid consumption, trace element concentration in the body, haematological values, femur morphometry data, gross necropsy and histopathology findings) were recorded in F1, F2 or F3 generation after different lengths of postnatal exposure (6 to 12 months). Results* show that the G and F effluents did not cause any specific health effect in rats, whereas the P effluent caused lower daily fluid consumption, decreased body weight at all stages of development, increased copper concentration in the carcass, smaller bones, atrophic organs and haemosiderosis in the liver. These changes might be related to the phenol content of this effluent.
Ključne riječi
Hrčak ID:
152900
URI
Datum izdavanja:
10.10.1988.
Posjeta: 1.154 *