Izvorni znanstveni članak

EFFECTS OF ANTI-OBSESSIONAL TREATMENT ON PITUITARY VOLUMES IN OBSESSIVE-COMPULSIVE DISORDER

Murad Atmaca ; Department of Psychiatry, School of Medicine, Firat University, Elazig, Turkey
Hanefi Yildirim ; Department of Radiology, School of Medicine, Firat University, Elazig, Turkey
Osman Mermi ; Department of Psychiatry, School of Medicine, Firat University, Elazig, Turkey
M. Gurkan Gurok ; Elazig Mental Health Hospital, Elazig, Turkey

Sažetak

Background: We aimed to examine the effct of anti-obsessional drugs on pituitary gland volumes in the patients with obsessivecompulsive
disorder (OCD).
Subjects and methods: A group of patients with OCD and of healthy controls were evaluated by using pituitary gland magnetic
resonance imaging (MRI) at baseline and after twelve weeks of treatment with selective serotonin re-uptake inhibitors or
clomipramine.
Results: Pituitary gland volumes were found to be statistically significantly smaller in the patients with OCD compared to
healthy control subjects at the beginning of the study. We found that pituitary volumes significantly increased throughout twelve
weeks of treatment.
Conclusions: This study provides an evidence of the effect of anti-obsessional treatment on the volumes of pituitary gland in
OCD patients.

Ključne riječi

anti-obsessional – OCD - pituitary gland - SSRI

Hrčak ID:

154756

URI

https://hrcak.srce.hr/154756

Datum izdavanja:

29.3.2016.

Posjeta: 1.436 *