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Frequency Distribution and Association of some Morpho- and Physiological Traits in Patients with Lung Diseases in Kosova

Avdulla J Alija ; Department of Biology, University of Prishtina, Prishtina, Kosovo
Ismet D Bajraktari ; Department of Biology, University of Prishtina, Prishtina, Kosovo
Nikolaus Bresgen ; Department of Cell Biology, University of Salzburg, Salzburg, Austria
Rifat Hadziselimovic ; Faculty of Science, University of Sarajevo,Sarajevo, Bosna and Herzegovina
Valentina Beqiraj ; Department of Biology, University of Prishtina, Prishtina, Kosovo
Mimoza Selimi ; Department of Biology, University of Prishtina, Prishtina, Kosovo
Hyrzeme Salihu ; Department of Biology, University of Prishtina, Prishtina, Kosovo
Besime Mikullovci ; Department of Biology, University of Prishtina, Prishtina, Kosovo
Peter Eckl ; Department of Cell Biology, University of Salzburg, Salzburg, Austria


Puni tekst: engleski pdf 760 Kb

str. 907-913

preuzimanja: 309

citiraj


Sažetak

The aim of this study was to investigate the distribution of specific phenotypes in patients with lung diseases as well as their eventual association withthe risk of developing lung diseases. For this purpose 2777 patients with lung diseases and 2778 healthy individuals from all over Kosova were examined for the appearance of the following selected phenotypes: ear lobe free (ELF)/ ear lobe attached, normal chin (NC)/cleft chin, tongue roller (TR)/non roller, hand clasping right thumb over (HC)/ hand clasping left thumb over, righthanded (RH)/lefthanded. In addition, the blood group from ABO system and the presence or absence of the Rhesus factor as phenotypical markers were observed. The results obtained show significant differences between control and lung disease patients for NC (P≤0.05) and TR (P≤0.005) as well as for blood groups AB (P≤0.05) and O (P≤0.005). These results point to eventually increased levels of genetic load as a result of the increased homozygosity in some gene loci causing an increased frequency of some recessive phenotypes in patients with lung diseases. Together with the specific associations observed, these preliminary findings could serve as a basis for further in depth investigations with respect to the types of lung diseases, occupational exposure and dietary habits, and thus is expected to contribute to an understanding of predispositions and susceptibility to lung diseases.

Ključne riječi

Lung diseases; phenotype; patients; susceptibility; Kosova

Hrčak ID:

166438

URI

https://hrcak.srce.hr/166438

Datum izdavanja:

15.12.2015.

Posjeta: 869 *