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THE RELEVANCE OF NEGATIVE SYMPTOMS IN SCHIZOPHRENIA AND HOW TO TREAT THEM WITH PSYCHOPHARMACEUTICALS?


Puni tekst: engleski pdf 80 Kb

str. 435-440

preuzimanja: 259

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Puni tekst: njemački pdf 80 Kb

str. 435-440

preuzimanja: 729

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Sažetak

Negative symptoms are highly prevalent in the acute
episode and long-term course of schizophrenia. They are often
persistent and tend to chronicity. They have an important
negative impact on different dimensions of outcome and
therefore require careful diagnosis and treatment. However,
the evidence for the available psychopharmacological
treatments is still not satisfactory and further research is
needed.
Antipsychotics, especially some second-generation antipsychotics,
are the primary treatment of choice, particularly
for negative symptoms in the acute episode. In case of residual
negative symptoms concomitant treatment with antidepressants
is often indicated. Glutamatergic compounds are of
great theoretical interest as an add-on treatment or even as a
monotherapy, but so far the efficacy results are inconsistent
and their clinical use is limited.

Ključne riječi

negative symptoms; schizophrenia; antipsychotics; antidepressants; glutamatergic compounds

Hrčak ID:

177179

URI

https://hrcak.srce.hr/177179

Datum izdavanja:

12.12.2016.

Podaci na drugim jezicima: njemački

Posjeta: 1.395 *