Izvorni znanstveni članak

Changes of the blood coagulation system of Holstein-Friesian heifers during the course of chlamydiosis

Przemysław Sobiech ; Department of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia-Mazury in Olsztyn,
Justyna Radwińska ; 1Department of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia-Mazury in Olsztyn,
Ryszard Targoński ; Department of Cardiology, City Hospital, Olsztyn, Poland
Anara Eleusizowa ; Department of Veterinary Sanitary, Faculty of Veterinary Sciences and Animal Husbandry, Kostanay State
Rauza Tuyakova ; Department of Veterinary Sanitary, Faculty of Veterinary Sciences and Animal Husbandry, Kostanay State
Katarzyna Żarczyńska ; Department of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia-Mazury in Olsztyn,
Agata Mitura ; Department of Cattle and Sheep Diseases, National Veterinary Research Institute in Pulawy, Puławy, Poland------
Anna Snarska ; Department of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia-Mazury in Olsztyn,

Sažetak

The objective of this study was to describe changes in the coagulation and fibrinolytic systems of Holstein-
Friesian (H-F) heifers infected naturally with Chlamydia spp. in Kazakhstan. Blood coagulation and morphology
tests were performed in 30 heifers, including 20 infected animals (experimental group I) and 10 clinically
healthy and uninfected animals (control group II). In the laboratory tests, the following blood parameters
were determined: prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT),
antithrombin III activity (ATIII), fibrinogen (FBG), D-dimer (D-D) concentrations, thrombocyte counts (PLT)
and leukocyte counts (WBC). Decreased PT and APTT values in the blood plasma of heifers infected with
Chlamydia spp. were indicative of intensified procoagulant activity in such an acute infection. Increased ATIII
activity could point to the activation of the anticoagulant system to prevent excessive fibrin production in
diseased animals. The results indicate that the hemostatic system was activated in heifers with symptoms of
chlamydiosis, and regulatory mechanisms prevented the development of life-threatening conditions such as
thrombosis or disseminated intravascular coagulation (DIC).Śő

Ključne riječi

chlamydiosis; hemostasis; fibrinolysis; cattle

Hrčak ID:

178515

URI

https://hrcak.srce.hr/178515

Datum izdavanja:

15.1.2017.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.356 *