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Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.

IVAN KOSALEC
MAJA ŠEGVIĆ KLARIĆ
STJEPAN PEPELJNJAK


Puni tekst: engleski pdf 87 Kb

str. 357-364

preuzimanja: 506

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Sažetak

Among airborne aspergilli sampled in outdoor air of the Zagreb area (2002/2003), Aspergillus niger (v. Teigh.) and A. fumigatus (Fres.) were the most abundant species (20-30%), with low mean annual concentrations (0.21-1.04 CFU m-3). Higher concentrations of A. fumigatus were observed in autumn and winter (0.5-1.05 CFU m-3) than in spring and summer (0-0.4 CFU m-3). On the other hand, A. fumigatus was found to be the most frequent isolate from upper and/or lower respiratory tracts of imunocompromised patients in many studies. This species produces several mycotoxins including the tremorgenic mycotoxin verruculogen that can be found in spores and during myceliar growth. Verruculogen production ability was tested by biosynthesis on 30 airborne and 33 clinical isolates of A. fumigatus. In both groups, high percentage of verruculogen-producing strains was noticed (84% of airborne and 91% of clinical isolates). Verruculogen production was not significantly different in the groups of airborne isolates (0.34 ± 0.16 mg mL-1) and clinical isolates (0.26 ± 0.19 mg mL-1, p > 0.05).

Ključne riječi

verruculogen, Aspergillus fumigatus, toxicity, mycotoxin, yeast extract

Hrčak ID:

18119

URI

https://hrcak.srce.hr/18119

Podaci na drugim jezicima: hrvatski

Posjeta: 1.011 *