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The mechanism of inhibition of esterases by organo-phosphorus compounds

W.N. Aldridge ; Medical Research Council, Toxicology Research Unit, Carshalton, England


Puni tekst: engleski pdf 10.368 Kb

str. 143-154

preuzimanja: 413

citiraj


Sažetak

A review is given of the present state of knowledge of the chemical nature of the reaction of esterases with organophosporus compounds. The phosphorylatiori process is known to be analogous to the normal hydrolysis of substrates. Reactivation by nucleophilic reagents and the nature of the conversion from reactivatable to the irreversible type of inhibition is discussed.

Ključne riječi

Hrčak ID:

183078

URI

https://hrcak.srce.hr/183078

Datum izdavanja:

23.6.1959.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.219 *