Croatica Chemica Acta, Vol. 90 No. 2, 2017.
Izvorni znanstveni članak
https://doi.org/10.5562/cca3162
Sensitive Electrochemical Determination of Folic Acid Using ex–situ Prepared Bismuth Film Electrodes
Nives Vladislavić
orcid.org/0000-0002-3185-6907
; Faculty of Chemistry and Technology, Department of General and Inorganic, Chemistry, University of Split, Split, Croatia
Marijo Buzuk
; Faculty of Chemistry and Technology, Department of General and Inorganic, Chemistry, University of Split, Split, Croatia
Maša Buljac
orcid.org/0000-0002-7518-8904
; Faculty of Chemistry and Technology, Department of Environmental Chemistry, University of Split, Split, Croatia
Stjepan Kožuh
; Faculty of Metallurgy, University of Zagreb, Sisak, Croatia
Marija Bralić
; Faculty of Chemistry and Technology, Department of Environmental Chemistry, University of Split, Split, Croatia
Slobodan Brinić
; Faculty of Chemistry and Technology, Department of General and Inorganic, Chemistry, University of Split, Split, Croatia
Sažetak
The electrochemical behavior of folic acid (FA), at the electrochemically prepared ex situ bismuth film (BiF) on glassy carbon electrode, clearly indicates electrocatalytic nature of the prepared film toward FA reduction (at –0.55 V). Scanning electron microscopy is used for morphological characterization of the prepared BiF. Accordingly, we establishing an electrochemical procedure based on square wave cathodic stripping voltammetry, preceded by accumulation of FA on the BiF electrode (BiFE). This analytical method is optimized and its analytical performance is presented. This electrode displays a two linear response range: 0.1 to 1.0 μmol L–1 and 1.0–10.0 μmol L–1 with sensitivity of 20.10 μA μmol–1 L and 2.28 μA μmol–1 L, respectively. Developed method was validated in compliance with spectrophotometric method. Excellent recovery and standard deviation obtained with BiFE revealed great analytical potential of the proposed method which was applied for the determination of FA in pharmaceuticals formulation.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Ključne riječi
bismuth film; folic acid; voltammetry; electroanalytical
Hrčak ID:
185683
URI
Datum izdavanja:
3.7.2017.
Posjeta: 2.488 *