Izvorni znanstveni članak
https://doi.org/10.20471/acc.2018.57.s1.05
Diagnostic Value of Cognitive-Registration Multiparametric Magnetic Resonance Guided Biopsy for the Detection of Prostate Cancer after Initial Negative Biopsy
Igor Tomašković
orcid.org/0000-0003-4182-9707
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Faculty of Medicine, Josip Juraj Strossmayer University, Osijek, Croatia; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Ivan Pezelj
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Karolina Bolanča Čulo
; Department of Radiology, Sestre milosrdnice University Hospital Center
Luka Novosel
; Department of Radiology, Sestre milosrdnice University Hospital Center
Sven Nikles
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Miroslav Tomić
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Ante Reljić
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Josip Katušić
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Matej Knežević
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Matea Pirša
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Božo Kruslin
; Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Center
Monika Ulamec
; Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Center
Boris Ružić
; Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb; Referral Center for Prostate Tumors of the Ministry of Health, Republic of Croatia
Sažetak
The aim of this prospective clinical study was to determine the detection rate of prostate cancers by multiparametric magnetic resonance and transrectal ultrasound (mpMRI-TRUS) cognitive fusion biopsies in patients with a previously negative TRUS-guided biopsy. Between 1 October 2016 and 1 July 2017, in 101 consecutive patients with elevated antigen (PSA) and/or positive digital rectal examination and after a negative first TRUS biopsy, a second, repeated prostate biopsy was performed. In 24 patients, cognitive fusion mpMRI-TRUS biopsy of the prostate with 8-10 system cores and 1-3 target biopsies was performed, in line with the European Association of Urology guidelines. In 77 patients, only a classic, repeated TRUS guided biopsy was performed. In patients with mpMRI, the detection rate according to PIRADS-v2 reporting system was: PIRADS 1, n = 0; PIRADS 2, n = 0; PIRADS 3, n = 0; PIRADS 4, n = 6/8 (75%); and PIRADS 5, n = 2/3 (67%). In the group of patients with MR-TRUS cognitive fusion biopsy, the prostate cancer detection rate was 8/24 (33%), while in the control group the detection rate was 12/77 (16%), which was statistically significant (t test, p = 0.037, CI 95% is 0.01 to 0.37). Patients with PIRADS ≤ 3 (54%) could have avoided the biopsy.
Ključne riječi
Prostate cancer; Multiparametric magnetic resonance; Biopsy
Hrčak ID:
207888
URI
Datum izdavanja:
1.10.2018.
Posjeta: 8.178 *