Croatica Chemica Acta, Vol. 34 No. 3, 1962.
Izvorni znanstveni članak
Studies in the Sphingolipids Series. XXIII. Synthesis and Resolution of erythro and threo "'C20-Sphingosines
B. Majhofer-Oreščanin
; Department of Biochemistry, Institute »Ruder Bo!ikovic«, Zagreb, Croatia, Yugoslavia
M. Proštenik
; Department of Biochemistry, Institute »Ruder Bo!ikovic«, Zagreb, Croatia, Yugoslavia
Sažetak
The synthesis of DL-trans-2-amino-11,3-dihydroxy-4-eicosenes (VII)
by condensation of 2-octadecyne-1- al (IV) with nitroethanol in ihe
presence of potassium carbonate and subsequent reduction of the
two nitrodiols (V) is described. The resolution of the DL-threo - base
(VIIa) into the optical isomers was effected with D-tartaric acid.
The DL - erythro-base (VIIb) was resolved with L-glutamic acid.
N atural C20-sphingosine i s most probably the trans-D( -t-) - erythrobase.
Ključne riječi
Hrčak ID:
208395
URI
Datum izdavanja:
25.11.1962.
Posjeta: 656 *